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Activators & Inhibitors

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    Results for Activators & Inhibitors ( 70851 )

      • GIP (1-30) amide, porcine

        Ref: T37588
        Sizes: 1 mg
        Price Enquiry

        GIP (1-30) amide, porcine (Legacy Tebubio ref. 282T37588). This GIP fragment has potent insulinotropic activity in the isolated, perfused rat pancreas but greatly reduced somatostatinotropic activity in the isolated perfused rat stomach. The site responsible for insulinotropic activity apparently lies between residues 19 and 30 of GIP.

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      • GIP (1-30) amide, porcine acetate

        Ref: T37588L
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg
        From: €90.00

        GIP (1-30) amide, porcine acetate (Legacy Tebubio ref. 282T37588L). GIP (1-30) amide, porcine acetate is an agonist of fully glucose-dependent insulinotropic polypeptide (GIP) receptor. GIP (1-30) amide, porcine acetate can weakly inhibit gastric acid secretion and strongly stimulate insulin.

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      • GIP (3-42), human

        Ref: T37589
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: €223.00

        GIP (3-42), human (Legacy Tebubio ref. 282T37589). GIP (3-42), human (Gastric Inhibitory Polypeptide (3-42) (human)) is a peptide that acts as a glucose-dependent proinsulinotropic polypeptide (GIP) receptor antagonist and regulates insulin secretion and the metabolic effects of GIP in vivo, which can be used to study type 2 diabetes.

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      • GIP (3-42), human acetate

        Ref: T37589L
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg
        Price Enquiry

        GIP (3-42), human acetate (Legacy Tebubio ref. 282T37589L). GIP (3-42), human acetate is an antagonist of a glucose-dependent insulinotropic polypeptide (GIP) receptor and regulates insulin secretion and GIP metabolism in vivo.

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      • 3,4-Dimethoxycinnamic acid

        Ref: T3759
        Sizes: 1 g, 500 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: €33.00

        3,4-Dimethoxycinnamic acid (Legacy Tebubio ref. 282T3759). 3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer found in *Securidaca inappendiculata* Hassk. It exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway.

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      • ML 3403

        Ref: T37590
        Sizes: 25 mg, 100 mg, 50 mg
        From: €1,726.00

        ML 3403 (Legacy Tebubio ref. 282T37590). p38 MAPK inhibitor (IC50 = 0.38 μM). Inhibits the release of IL-1β and TNF-α in a peripheral blood mononuclear cell (PBMC) assay (IC50 values are 0.039 and 0.16 μM respectively).

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      • IMP-1710

        Ref: T37591
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: €339.00

        IMP-1710 (Legacy Tebubio ref. 282T37591). IMP-1710 is a selective UCH-L1 inhibitor with an IC50 value of 38 nM in a fluorescence polarization assay.IMP-1710 has antifibrotic activity. [1]

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      • Pericosine A

        Ref: T37594
        Sizes: 1 mg
        From: €781.00

        Pericosine A (Legacy Tebubio ref. 282T37594). Pericosine A is a fungal metabolite that has been found inP. byssoidesand has anticancer activity.1It inhibits the growth of a variety of cancer cells, including breast, colon, lung, ovary, stomach, and prostate cell lines (GI50s = 0.05-24.55 μM) and increases survival in a P388 mouse xenograft model when administered at a dose of 25 mg/kg. Pericosine A inhibits EGFR by 40 to 70% when used at a concentration of 100 μg/ml. It also reacts with organosulfur compounds in skunk spray to form stable thioethers as odorless products.2

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      • Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine

        Ref: T37595
        Sizes: 1 mg
        From: €364.00

        Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt) (Legacy Tebubio ref. 282T37595). Brain-derived acidic fibroblast growth factor (brain-derived aFGF) (1-11) is a peptide fragment of brain-derived aFGF. Brain-derived aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that has sequence homology to interleukin-1. aFGF (1-11) corresponds to amino acid residues 1-11 of the full length peptide.

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