Activators & Inhibitors

Stearoyl-L-carnitine chloride (Legacy Tebubio ref. 282T37735). Stearoyl-L-carnitine chloride (Acylcarnitine C18:0) is a long-chain acylcarnitine found in the cerebellum that inhibits GlyT2 and is an important component in the study of lipid metabolism.

N-cis-hexadec-9Z-enoyl-L-Homoserine lactone (Legacy Tebubio ref. 282T37736). Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.[2] Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group) and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family.[3] C16:1-Δ9-(L)-HSL is a long-ch

N-cis-octadec-9Z-enoyl-L-Homoserine lactone (Legacy Tebubio ref. 282T37737). Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group) and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family. C18:1-δ9 cis-(L)-HSL is a long-chain A

N-cis-tetradec-9Z-enoyl-L-Homoserine lactone (Legacy Tebubio ref. 282T37738). Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group) and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family. C14:1-δ9-cis-(L)-HSL is a long-chain

N-decanoyl-L-Homoserine lactone (Legacy Tebubio ref. 282T37739). N-decanoyl-L-Homoserine lactone (C10-HSL) is an N-acyl-homoserine lactone (AHL) produced by Pseudomonas cremoris strain ND07.N-decanoyl-L-homoserine lactone inhibits the growth of primary roots of Arabidopsis thaliana.N-decanoyl-L-homoserine lactone treatment caused a transient and immediate increase in free Ca2+ and reactive oxygen species (ROS) concentrations in the root cytoplasm. N-decanoyl-L-homoserine lactone treatment induced transient and immediate increases in cytoplasmic free Ca2+ and reactive oxygen species (ROS) concentrations in Arabidopsis roots, increased mitogen-activated protein kinase 6 (MPK6) activity, and contributed to the production of nitric oxide (NO).

Gracillin (Legacy Tebubio ref. 282T3774). Gracillin can induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells, and has the potential to be developed as an antitumor agent. Gracillin can be selected as lead compounds for the development of new drugs against I. multifiliis.

N-Demethylvancomycin (hydrochloride) (Legacy Tebubio ref. 282T37740). N-Demethylvancomycin is a glycopeptide antibiotic that has been found inNocardia orientalis.1It is active against several strains ofS. aureusandS. epidermidisin vitroandin vivo.2Formulations containing N-demethylvancomycin have been used in the treatment of bacterial infections.

N-hexadecanoyl-L-Homoserine lactone (Legacy Tebubio ref. 282T37741). Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.[2] Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). Regulation of bacterial quorum sensing signaling systems to inhibit pathogenesis represents a new approach to antimicrobial therapy in the treatment of infectious diseases.[3] AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group), and in the presence or absence of one or more carbon-carbon double bonds in t

N-hexanoyl-DL-Homoserine lactone (Legacy Tebubio ref. 282T37742). N-hexanoyl-DL-Homoserine lactone (C6-HSL), isolated from bivalve larval cultures, degrades bacteria and inhibits lesions induced by the phytopathogenic fungus B. cinerea.N-hexanoyl-DL-Homoserine lactone participates in the bacterial N-acyl-homoserine lactone (AHL) community-sensing (QS) system. N-hexanoyl-DL-Homoserine lactone is involved in the N-acyl-homoserine lactone (AHL) community sensing (QS) system between bacteria.