Skip to main content
Customer Service: +351 215 842 958
Contact us
(0)
My Wishlist
(0)
My Wishlist
(0)
My WishlistContact us
Products banner

Activators & Inhibitors

Filters

    Results for Activators & Inhibitors ( 70848 )

      • M 084 hydrochloride

        Ref: T37823
        Sizes: 50 mg, 10 mg
        Price Enquiry

        M 084 hydrochloride (Legacy Tebubio ref. 282T37823). TRPC4/5 channel blocker (IC50 values are 3.7-10.3 and 8.2 μM, respectively). Also weakly blocks TRPC3 channels. Exhibits rapid antidepressant and anxiolytic effects in vivo.

        Product detail

      • MSC-4381

        Ref: T37824
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: €73.00

        MSC-4381 (Legacy Tebubio ref. 282T37824). MSC-4381 (MCT4-IN-1) is an orally available and selectively modeled highly potent inhibitor of monocarboxylic acid transporter protein 4 (MCT4/SLC16A3) with potential anticancer and antitumor activity for the study of osteosarcoma.

        Product detail

      • CAY10434

        Ref: T37825
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg
        From: €40.00

        CAY10434 (Legacy Tebubio ref. 282T37825). CAY10434 is an active inhibitor of CYP4A hydroxylase with an IC50 value of 8.8 nM in human kidney microsomal test. The maximum contractile value (Emax) of CAY 10434 was 6764 mg in improving the contractile process of angiotensin II.

        Product detail

      • CAY10462

        Ref: T37826
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 2 mg
        From: €33.00

        CAY10462 (Legacy Tebubio ref. 282T37826). CAY10462 (CTK8E8405) is an effective and selective inhibitor of the 20-HETE synthase CYP4A11 with an IC50 of 8.8 nM. CAY10462 exhibits nearly 200 times less potent for 1A, 1C, and 3A CYP450 enzymes.

        Product detail

      • CAY10506

        Ref: T37827
        Sizes: 10 mg
        From: €969.00

        CAY10506 (Legacy Tebubio ref. 282T37827). Anti-diabetic drugs of the thiazolidinedione (TZD) structural class as well as α-lipoic acid activate peroxisome proliferator-activated receptor γ (PPARγ), a nuclear transcription factor that controls glucose metabolism and lipid homeostasis. CAY10506 is a hybrid lipoic acid-TZD derivative that transactivates human PPARγ with an EC50 value of 10 μM.

        Product detail

      • CAY10514

        Ref: T37828
        Sizes: 1 mg, 5 mg, 50 mg, 10 mg
        From: €72.00

        CAY10514 (Legacy Tebubio ref. 282T37828). CAY10514 is an aromatic analog of 8(S)-HETE. It acts as a dual agonist of PPARα and PPARγ with EC50 values of 0.173 and 0.642 μM, respectively.

        Product detail

      • CAY10573

        Ref: T37829
        Sizes: 1 mg, 5 mg, 10 mg
        From: €239.00

        CAY10573 (Legacy Tebubio ref. 282T37829). The peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors often used as drug targets for the treatment of metabolic disorders. CAY10573 is a PPAR agonist that displays potent binding at PPARα, γ, and δ with IC50 values of 113, 50, and 223 nM, respectively. It potently transactivates PPARα, γ, and δ with EC50 values of 8, 70, and 500 nM, respectively. CAY10573 demonstrates stronger binding and functional activity for PPARγ than the antidiabetic compound rosiglitazone (IC50 = 92 nM; EC50 = 220 nM).

        Product detail

      • Fraxin

        Ref: T3783
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: €37.00

        Fraxin (Legacy Tebubio ref. 282T3783). Fraxin (Fraxoside) is a glucoside of fraxetin.

        Product detail

      • CAY10599

        Ref: T37830
        Sizes: 1 mg, 5 mg, 10 mg, 500 μg
        From: €125.00

        CAY10599 (Legacy Tebubio ref. 282T37830). CAY10599 has a wide range of applications in life science related research.

        Product detail