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Activators & Inhibitors

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    Results for Activators & Inhibitors ( 18112 )

      • Fmoc-Val-Cit-PAB

        Ref: T4678
        Sizes: 25 mg
        From: €33.00

        Fmoc-Val-Cit-PAB (Legacy Tebubio ref. 282T4678). Fmoc-Val-Cit-PAB is a linker used for antibody-drug-conjugation (ADC).

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      • WM-1119

        Ref: T4679
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: €54.00

        WM-1119 (Legacy Tebubio ref. 282T4679). WM-1119 is a highly potent, selective KAT6A/B inhibitor

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      • HC-067047

        Ref: T4680
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: €35.00

        HC-067047 (Legacy Tebubio ref. 282T4680). HC-067047 is a potent and selective TRPV4 antagonist that also inhibits the endogenous TRPV4-mediated response to 4α-PDH.

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      • HC067047 Hydrochloride(883031-03-6 free base)

        Ref: T4680L
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: €91.00

        HC067047 Hydrochloride(883031-03-6 free base) (Legacy Tebubio ref. 282T4680L). HC-067047 hydrochloride is a potent and selective TRPV4 antagonist, effectively and reversibly inhibiting currents through human, rat, and mouse TRPV4 orthologs with IC50 values of 486 nM, 133 nM, and 17 nM, respectively.

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      • T863

        Ref: T4681
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: €37.00

        T863 (Legacy Tebubio ref. 282T4681). T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells. IC50 value: Target: DGAT1 T863 (DGAT-3) causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice.

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      • Alovudine

        Ref: T4683
        Sizes: 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: €35.00

        Alovudine (Legacy Tebubio ref. 282T4683). Alovudine (3'-Deoxy-3'-fluorothymidine) is a marker of DNA synthesis. Alovudine is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and is a better biomarker in pancreatic cancer.

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      • ML241 hydrochloride

        Ref: T4684
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: €54.00

        ML241 hydrochloride (Legacy Tebubio ref. 282T4684). ML241 is a potent and selective inhibitors of p97 ATPase.ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. ML241 may be a novel agent for the chemotherapy of cancer, and provide a rationale for developing pathway-specific p97 inhibitors.

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      • INOSINIC ACID

        Ref: T4685
        Sizes: 25 mg, 100 mg, 50 mg, 1 mL * 10 mM (in DMSO)
        From: €47.00

        INOSINIC ACID (Legacy Tebubio ref. 282T4685). Inosinic acid (IMP) is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Inosinic acid is a nucleotide present in muscle and other tissues. It is formed by the deamination of AMP and when hydrolysed produces inosine. Inosinic acid is the ribonucleotide of hypoxanthine and is the first compound formed during the synthesis of purine.Inosine 5′-monophosphate (IMP) is used as a substrate to study the distribution, specificity and kinetics of inosine-5′-monophosphate dehydrogenase (IMPDH).

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      • Simeprevir

        Ref: T4686
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: €35.00

        Simeprevir (Legacy Tebubio ref. 282T4686). Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.

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