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Activators & Inhibitors

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    Results for Activators & Inhibitors ( 18112 )

      • Ro5-3335

        Ref: T4687
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: €48.00

        Ro5-3335 (Legacy Tebubio ref. 282T4687). Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins (IC50 = 1.1 μM). Ro5-3335 represses RUNX1/CBFβ-dependent transactivation in reporter assays and inhibits transcriptional regulation by RUNX1 and CBFβ. Ro5-3335 also reduces the leukemia burden in a mouse model. Attenuates RUNX1-dependent hematopoiesis in zebrafish embryos. It also is a Tat antagonist and inhibits HIV-1 replication in vitro.

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      • Pipequaline hydrochloride

        Ref: T4688
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: €47.00

        Pipequaline hydrochloride (Legacy Tebubio ref. 282T4688). Pipequaline hydrochloride (PK-8165 hydrochloride) is an anticonflict and anticonvulsant quinoline derivative and an anxiolytic drug that was never marketed. It possesses a novel chemical structure, not closely related to other drugs of this type, with a pharmacological profile similar to benzodiazepines but predominantly anxiolytic, exhibiting minimal sedative, amnestic, or anticonvulsant effects, thus classified as a nonbenzodiazepine anxiolytic.

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      • Palosuran hydrochloride 540769-28-6(free base）

        Ref: T4689
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        Price Enquiry

        Palosuran hydrochloride 540769-28-6(free base） (Legacy Tebubio ref. 282T4689). Palosuran hydrochloride 540769-28-6(free base)(ACT-058362 hydrochloride) is a new potent and specific antagonist of the human UT receptor with an IC50 of 3.6±0.2 nM.

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      • Betrixaban hydrochloride(330942-05-7(free base))

        Ref: T4690
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: €46.00

        Betrixaban hydrochloride(330942-05-7(free base)) (Legacy Tebubio ref. 282T4690). Betrixaban hydrochloride(330942-05-7(free base)) (PRT054021 hydrochloride) is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5 nM).

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      • Asimadoline hydrochloride

        Ref: T4691
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: €35.00

        Asimadoline hydrochloride (Legacy Tebubio ref. 282T4691). Asimadoline hydrochloride (EMD-61753 hydrochloride) is a κ-opioid receptor agonist potentially for the treatment of pruritus. Asimadoline hydrochloride has also been shown to be used in the treatment of irritable bowel syndrome.

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      • Protein kinase inhibitors 1 hydrochlorid

        Ref: T4692
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 2 mg
        From: €42.00

        Protein kinase inhibitors 1 hydrochlorid (Legacy Tebubio ref. 282T4692). Protein kinase inhibitors 1 hydrochlorid (Protein kinase inhibitors 1 hydrochlorid (1365986-44-2(free base))) is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.

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      • 2-Aminoethyl diphenylborinate

        Ref: T4693
        Sizes: 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: €33.00

        2-Aminoethyl diphenylborinate (Legacy Tebubio ref. 282T4693). 2-Aminoethyl diphenylborinate (2-APB) is a chemical compound that inhibits IP3 receptors and TRP channels, though it activates TRPV1, TRPV2, and TRPV3 at higher concentrations.

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      • AG-1557 hydrochloride (189290-58-2(free base))

        Ref: T4694
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg
        From: €35.00

        AG-1557 hydrochloride (189290-58-2(free base)) (Legacy Tebubio ref. 282T4694). AG-1557 hydrochloride is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).

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      • CP671305

        Ref: T4695
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: €36.00

        CP671305 (Legacy Tebubio ref. 282T4695). CP671305 is an orally active, potent and selective inhibitor of phosphodiesterase-4-D.

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