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    Results for Activators & Inhibitors ( 70846 )

      • Ref: T38163
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: €63.00

        ML-148 (Legacy Tebubio ref. 282T38163). ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM). ML-148 can be used to profile across a panel of related dehydrogenase or reductase enzymes and in studies about prostaglandin-signaling pathways.

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      • Ref: T38164
        Sizes: 25 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: €39.00

        MnTBAP chloride (Legacy Tebubio ref. 282T38164). MnTBAP chloride (Mn(III)TBAP) is a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger that reduces the doubling time of SOD-E. coli by a factor of 2. MnTBAP chloride exhibits anti-inflammatory effects through upregulation of BMPR-II and inhibition of NFκB signaling. mnTBAP chloride is a manganese porphyrin complex with antioxidant properties and has potential for use in the study of fibrotic responses in chronic kidney diseases (CKDs).

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      • Ref: T38165
        Sizes: 1 mg, 5 mg

        FBBBE (Legacy Tebubio ref. 282T38165). FBBBE is a derivatized fluorescein compound that is used to detect the production hydrogen peroxide (H2O2) by cells. Intracellular H2O2, but not extracellular H2O2, initiates the conversion of FBBBE to fluorescein, resulting in an increase in intracellular fluorescence (excitation/emission maxima: 480/512 nm).

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      • Ref: T38166
        Sizes: 10 mg
        From: €975.00

        Ferrioxamine E (Legacy Tebubio ref. 282T38166). Ferrioxamine E is an iron supplement used by both Salmonella and Escherichia coli, a growth promoter for detecting Salmonella in food and industrial applications.

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      • Ref: T38167
        Sizes: 1 mg
        From: €952.00

        BE-24566B (Legacy Tebubio ref. 282T38167). BE-24566B is a polyketide fungal metabolite originally isolated fromS. violaceusniger.1It is active againstB. subtilis,B. cereus,S. aureus,M. luteus,E. faecalis, andS. thermophilus(MICs = 1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 μg/ml, respectively). BE-24566B is an endothelin (ET) receptor antagonist (IC50s = 11 and 3.9 μM for ETAand ETBreceptors, respectively).2

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      • Ref: T38168
        Sizes: 100 mg, 50 mg
        From: €857.00

        S.pombe lumazine synthase-IN-1 (Legacy Tebubio ref. 282T38168). S.pombe lumazine synthase-IN-1 is a compound that inhibits lumazine synthases, with Ki values of 243 μM for Schizosaccharomyces pombe and 9.6 μM for Mycobacterium tuberculosis, respectively[1].

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      • Ref: T38169
        Sizes: 1 mg, 10 mg
        From: €447.00

        LY 341495 disodium salt (Legacy Tebubio ref. 282T38169). Highly potent and selective group II metabotropic glutamate receptor antagonist. Disodium salt of LY 341495

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      • Ref: T3817
        Sizes: 1 mg, 5 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: €111.00

        Darutigenol (Legacy Tebubio ref. 282T3817). Darutigenol has obvious antithrombotic effect, its mechanism may be related to inhibition of platelet aggregation and adhesion.

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      • Ref: T38170
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: €168.00

        RMC-0331 (Legacy Tebubio ref. 282T38170). RMC-0331 (RM-023) is an orally available and potent SOS1 inhibitor with potential anticancer activity, blocking RAS activation by disrupting RAS-SOS1 interactions.

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