Skip to main content
Customer Service: +351 215 842 958
Contact us
(0)
My Wishlist
(0)
My Wishlist
(0)
My WishlistContact us
Products banner

Activators & Inhibitors

Filters

    Results for Activators & Inhibitors ( 70847 )

      • NS13001

        Ref: T16345
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: €52.00

        NS13001 (Legacy Tebubio ref. 282T16345). NS13001 (N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine) is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels). The EC50s are 1.8 and 0.14 μM for SK2 and SK3, respectively. NS13001 holds promise as a potential therapeutic agent for treatment of spinocerebellar ataxia type 2 (SCA2) and possibly other cerebellar ataxias.

        Product detail

      • NS1652

        Ref: T16346
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg
        From: €91.00

        NS1652 (Legacy Tebubio ref. 282T16346). NS1652 is an anion conductance inhibitor. NS1652 blocks chloride channel has an IC50 of 1.6 μM in human and mouse red blood cells.

        Product detail

      • NS3623

        Ref: T16347
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: €33.00

        NS3623 (Legacy Tebubio ref. 282T16347). NS3623 is an activator of human ether-a-go-go-related gene (hERG) potassium channels with a dual mode of action, also acting as an inhibitor of hERG1 channels. It activates the IKr and Ito currents and exhibits an antiarrhythmic effect.

        Product detail

      • NS5806

        Ref: T16348
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: €39.00

        NS5806 (Legacy Tebubio ref. 282T16348). NS5806 is an effective potassium current activator. NS5806 slows KV4.3 and KV4.2 current decay in channel complexes containing KChIP2. NS5806 enhances KV4.3/KChIP2 peak current amplitudes (EC50: 5.3 μM).

        Product detail

      • NSC-60339

        Ref: T16349
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg
        From: €84.00

        NSC-60339 (Legacy Tebubio ref. 282T16349). NSC-60339 is an inhibitor of efflux pump, and a substrate of AcrAB-TolC, is a polybasic terephthalic acid derivative studied as a potential cancer chemotherapeutic agent.

        Product detail

      • Fenchlorphos

        Ref: T1635
        Sizes: 25 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: €55.00

        Fenchlorphos (Legacy Tebubio ref. 282T1635). Fenchlorphos (Dermafos) is a cholinesterase inhibitor, used as an insecticide.

        Product detail

      • NSC-87877

        Ref: T16350
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: €54.00

        NSC-87877 (Legacy Tebubio ref. 282T16350). NSC-87877 is an effective inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (IC50=0.318 μM, 0.355 μM of shp2 and shp1, respectively).It also inhibits dual-specificity phosphatase 26 (DUSP26).

        Product detail

      • NSC16168

        Ref: T16351
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: €66.00

        NSC16168 (Legacy Tebubio ref. 282T16351). NSC16168 is a selective ERCC1-XPF inhibitor that inhibits DNA repair and potentiates the antitumor activity of cisplatin.

        Product detail

      • Meseclazone

        Ref: T16353
        Sizes: 25 mg, 100 mg, 50 mg
        From: €1,726.00

        Meseclazone (Legacy Tebubio ref. 282T16353). Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.

        Product detail