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Results for Activators & Inhibitors ( 70847 )
- From: €272.00
NSC745885 (Legacy Tebubio ref. 282T16354). NSC745885 is an effective down-regulator of EZH2 via proteasome-mediated degradation. NSC745885 is also an effective anti-tumor agent that displays selective toxicity against multiple cancer cell lines but not normal cells. NSC745885 offers possibilities for the study of advanced bladder and oral squamous cell carcinoma (OSCC) cancers.
- From: €40.00
NU6140 (Legacy Tebubio ref. 282T16359). NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM). It shows 10- to 36-fold selectivity over other CDKs. NU6140 also effectively inhibits Aurora A and Aurora B (IC50s: 67 and 35 nM, respectively). It also enhances the apoptotic effect and has anti-cancer activity.
- Ref: T1636Sizes: 25 mg, 100 mg, 50 mg, 500 mg, 200 mg, 1 mL * 10 mM (in DMSO)