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Activators & Inhibitors

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    Results for Activators & Inhibitors ( 70847 )

      • Okadaic acid

        Ref: T16381
        Sizes: 25 μg, 100 μg, 50 μg
        From: €163.00

        Okadaic acid (Legacy Tebubio ref. 282T16381). Okadaic acid is a potent polyether marine toxin that accumulates in the digestive glands of marine mollusks.Okadaic acid is a highly potent and selective protein phosphatase (PP) inhibitor, inhibiting PP1, PP2A, PP3, PP4, and PP5.Okadaic acid activates Wnt/β-catenin signaling in human HepaRG cells. catenin signaling in human HepaRG cells.

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      • Olinciguat

        Ref: T16383
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: €214.00

        Olinciguat (Legacy Tebubio ref. 282T16383). Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator. It also has concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole-cell assay.

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      • Olutasidenib

        Ref: T16384
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: €64.00

        Olutasidenib (Legacy Tebubio ref. 282T16384). Olutasidenib (FT-2102) is under the study in the treatment of acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). Olutasidenib is a highly effective, brain penetrant, and selective inhibitor of the mutant Isocitrate dehydrogenase 1 (IDH1) (IC50: 21.2 nM and 114 nM for IDH1- R132H and IDH1- R132C, respectively).

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      • Omapatrilat

        Ref: T16385
        Sizes: 100 mg, 2 mg
        From: €70.00

        Omapatrilat (Legacy Tebubio ref. 282T16385). Omapatrilat is a metalloprotease ACE and NEP dual inhibitor (Ki: 0.64 and 0.45 nM, respectively).

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      • Ombrabulin hydrochloride

        Ref: T16386
        Sizes: 2 mg
        From: €53.00

        Ombrabulin hydrochloride (Legacy Tebubio ref. 282T16386). Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and has antivascular effects. Ombrabulin is a tubulin polymerizing inhibitor, a member of the combretastatin A-4 compound class, which is a water-soluble tubulin depolymerizing tumor vascularizing compound.

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      • Omidenepag isopropyl

        Ref: T16388
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: €60.00

        Omidenepag isopropyl (Legacy Tebubio ref. 282T16388). Omidenepag isopropyl (DE-117) is a selective prostaglandin EP2 receptor agonist and a novel topical ocular blood pressure lowering compound.Omidenepag isopropyl has a weak affinity for EP1, EP2, and FP receptors.Omidenepag isopropyl is used in studies of glaucoma and hypertension. Omidenepag isopropyl can be used to study glaucoma and hypertension.

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      • Omidenepag

        Ref: T16389
        Sizes: 1 mg
        From: €79.00

        Omidenepag (Legacy Tebubio ref. 282T16389). Omidenepag (UR-7276) is a selective and potent prostaglandin E2 receptor 2 (EP2) agonist and a novel topical ocular hypotensive agent.Omidenepag is used in the study of glaucoma and hypertension.

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      • Amlexanox

        Ref: T1639
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 1 mL * 10 mM (in DMSO)
        From: €37.00

        Amlexanox (Legacy Tebubio ref. 282T1639). Amlexanox (AA673) is an anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexanox also acts as a leukotriene D4 antagonist and a phosphodiesterase inhibitor. Amlexanox decreases the time ulcers take to heal as well as the pain associated with the ulcers.

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      • ON-013100

        Ref: T16391
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: €49.00

        ON-013100 (Legacy Tebubio ref. 282T16391). ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.

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