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Activators & Inhibitors

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    Results for Activators & Inhibitors ( 70847 )

      • Rabeprazole sodium

        Ref: T1651
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: €35.00

        Rabeprazole sodium (Legacy Tebubio ref. 282T1651). Rabeprazole sodium (Habeprazole Sodium) is a 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of stomach ulcers and Zollinger-Ellison syndrome. The drug inhibits H(+)-K(+)-exchanging ATPase which is found in gastric parietal cells.

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      • PF-915275

        Ref: T16510
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: €37.00

        PF-915275 (Legacy Tebubio ref. 282T16510). PF-915275 is an effective and selective inhibitor of human 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1, Ki = 2.3 nM, EC50 = 15 nM in vitro HEK293 cells). The dose-dependent effect of PF-915275 on conversion of cortisone to cortisol in primary human and monkey hepatocytes, with an EC50 of 20 and 100 nM, respectively.

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      • PF2562

        Ref: T16511
        Sizes: 25 mg, 100 mg, 50 mg
        From: €1,726.00

        PF2562 (Legacy Tebubio ref. 282T16511). PF2562 is a dopamine D1 ligand. It is used as a dopamine D1 agonist or partial agonist. PF2562 binds to human D1 receptor (Ki: 113 nM). PF2562 shows activity against human D1 cAMP (EC50: 568 nM in HTRF assay).

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      • PFE-360

        Ref: T16512
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 2 mg
        From: €78.00

        PFE-360 (Legacy Tebubio ref. 282T16512). PFE-360 (PF-06685360) is a potent and selective inhibitor of LRRK2 kinase, with an in vivo IC50 of 2.3 nM.

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      • PF 03709270

        Ref: T16513
        Sizes: 25 mg, 100 mg, 50 mg
        From: €3,258.00

        PF 03709270 (Legacy Tebubio ref. 282T16513). PF 03709270 is an orally available ester prodrug form of sulopenem. It has broad-spectrum antibacterial activity against most gram-positive and gram-negative bacteria.

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      • PF 04531083

        Ref: T16514
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: €39.00

        PF 04531083 (Legacy Tebubio ref. 282T16514). PF 04531083 is a selective blocker of the NaV1.8 channel. PF 04531083 can be used for neuropathic and inflammatory pain studies.

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      • PF 750

        Ref: T16515
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 200 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: €38.00

        PF 750 (Legacy Tebubio ref. 282T16515). PF 750 (ZINC27647189) is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.

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      • PG01

        Ref: T16516
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: €144.00

        PG01 (Legacy Tebubio ref. 282T16516). PG01 is a potent CFTR Cl-channel potentiator, effective against ΔF508 (Ka 0.3 μM), and also against E193K, G970R and G551D (CFTR mutants), with Kd values of 0.22 μM, 0.45 μM and 1.94 μM, respectively.PG01 increases ΔF508-CFTR Cl- currents upon addition of forskolin. F508-CFTR Cl-current upon addition of Forskolin, correcting the gating defect of CFTR mutants.

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      • PGMI-004A

        Ref: T16517
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg
        From: €394.00

        PGMI-004A (Legacy Tebubio ref. 282T16517). PGMI-004A is an effective inhibitor of phosphoglycerate mutase 1 (IC50: 13.1 μM).

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