Results for Activators & Inhibitors ( 86779 )
- From: €41.00
Protein acetylation is a common posttranslational modification that plays a crucial role in regulating biological processes such as gene expression, cell proliferation, and metabolic regulation. The acetylation level of proteins within cells is regulated by both acetyltransferases and deacetylases. Deacetylase inhibitors can effectively prevent the loss of acetylation modifications to increase the acetylation level. TargetMol deacetylase inhibitor cocktail consists of four components that effectively inhibit the activity of various deacetylases and maintain protein acetylation status, including reversible inhibitors for Class I/II deacetylases such as Trichostatin A and Sodium Butyrate, a reversible inhibitor for Class III deacetylases (sirtuins, SIRTs) like Nicotinamide, and a selective reversible inhibitor for SIRT1, known as EX-527. To enhance the detection of protein acetylation level, deacetylase inhibitor cocktail can be added to cell culture medium for a certain incubation perio
- From: €30.00
The production and breakdown of intracellular proteins is in dynamic equilibrium under stable environmental conditions and when proteins are extracted from cells and tissues in vitro, crude cell extracts contain many endogenous enzymes that are capable of degrading the target proteins, e.g. phosphatases and proteases. These enzymes are released from the cells or activated, leading to the breakdown of the target protein and affecting the results of the analysis. To avoid this, one way to increase the yield of target proteins is to incorporate inhibitors of the relevant enzymes. TargetMol Mass Spectrometry-Compatible Protease Inhibitor Cocktail has a solvent of ddH2O and consists of four components including Aprotinin, Bestatin, E-64 and Leupeptin, which have broad specificity for serine and cysteine proteases and aminopeptidases, and no EDTA. This product is free of AEBSF, which avoids the potential for peak drift in mass spectra. This product does not contain AEBSF, thus avoiding the p
- Ref: C0056Sizes: 1 mL, 1 mL * 10, 1 mL * 100, 1 mL * 50From: €32.00
The production and breakdown of intracellular proteins is in dynamic equilibrium under stable environmental conditions and when proteins are extracted from cells and tissues in vitro, crude cell extracts contain many endogenous enzymes that are capable of degrading the target proteins, e.g. phosphatases and proteases. These enzymes are released from the cells or are activated, leading to the breakdown of the target protein and affecting the results of the analysis. Therefore, adding appropriate inhibitors of proteases, phosphatases and other enzymes to the extracts is an effective way to prevent protein degradation and de-modification. TargetMol Protease Phosphatase Inhibitor Cocktail is a mixture of 5 protease inhibitors and 4 phosphatase inhibitors in ddH2O, which can efficiently inhibit a wide range of proteases including serine, cysteine proteases, and aminopeptidases, as well as a wide range of phosphatases including acid, alkaline, and serine/threonine phosphatases in protein ext
- Ref: C0057Sizes: 1 mL, 1 mL * 10, 1 mL * 100, 1 mL * 50From: €44.00
The production and breakdown of intracellular proteins is in dynamic equilibrium under stable environmental conditions and when proteins are extracted from cells and tissues in vitro, crude cell extracts contain many endogenous enzymes that are capable of degrading the target proteins, e.g. phosphatases and proteases. These enzymes are released from the cells or are activated, leading to the breakdown of the target protein and affecting the results of the analysis. Therefore, adding appropriate inhibitors of proteases, phosphatases and other enzymes to the extracts is an effective way to prevent protein degradation and de-modification. TargetMol Protease Phosphatase Inhibitor Cocktail, with ddH2O as solvent, is a mixture of 4 protease inhibitors and 4 phosphatase inhibitors, which can efficiently inhibit a variety of proteases including serine, cysteine proteases and aminopeptidases, as well as a variety of phosphatases including acidic, alkaline, and serine/threonine phosphatases in p
- Ref: Fr12622Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg