Compound Libraries

- 400 active small molecules associated with cuproptosis for high-throughput and high-intensity screening. - Targeting Ferredoxin 1 (FDX1), Antioxidant 1 Copper Chaperone (ATOX1), CCS (copper chaperones), mitochondrial respiration, etc. - Some compounds are FDA-approved. - Detailed instructions, compound structure, target information, description of activity, etc. - Various detection techniques such as NMR, HPLC/LCMS to ensure the correct structure and high purity of the product and reduce false positives.

DNA-Encoded Chemical Library (GenDECL) kit,4vials (5 nmol/vial)

- 555 glycolysis-related active compounds for high-throughput and high-content screening. - Targets of action include hexokinase; pyruvate kinase; glucokinase and other key enzymes of glycolysis. - Detailed instructions, compound structure, target information, activity description, etc. - NMR and HPLC detection techniques to ensure high product purity and quality. - All compounds are available in stock.

- A unique collection of 3059 metabolic pathway-related bioactive small molecule compounds for high-throughput, high-content screening. - Targeting multiple metabolic pathways such as gluconeogenesis, lipid metabolism, nucleotide metabolism; targets include GLUT, Hexokinase, Pyruvate Kinase; ATGL, MAGL, FAAH and other metabolism-related popular targets. - Structural diversity, significant drug potency and cell penetration. - Detailed specifications, compound structure, target information, activity description, etc. - NMR, HPLC/LCMS and other detection techniques to ensure correct structure and high purity of the product and reduce false positives.

- A unique collection of 288 compounds (TCM monomers) with antiviral activity,is a powerful tool for drug development and pharmacological study; - Diversified structures including Flavonoids, Saponin,Terpenes, Alkaloids,etc.; - Target viruses include SARS-CoV, Influenza Virus, HBV, HCV, HIV, HSV, etc.; - Various detection techniques such as NMR, HPLC/LCMS to ensure the correct structure and high purity of the products and reduce false positives.

- 1066 types of active small molecules associated with pyroptosis for high-throughput and high-content screening. - Targets include Caspase-1, Caspase-4, Caspase-5, Caspase-11, NLRP3, gasdermin D, etc. - Some compounds have been FDA-approved. - Detailed specifications, compound structures, target information, activity descriptions, etc. - Various detection techniques such as NMR, HPLC/LCMS to ensure the correct structure and high purity of the product and reduce false positives.

- A unique collection of 972 pediatric drugs for high-throughput screening and high-content screening. - All drugs are either approved for marketing or in clinical trials with validated biological activity and safety. - Can be used for functional repositioning of drugs to discover new pediatric indications. - Detailed instructions, compound structures, target information, activity descriptions, etc. - NMR and HPLC detection techniques to ensure high product purity. - All compounds are available in stock.

Key features: The mean Tanimoto value of the 50k Diversity Set PS8 is 0.898, with even lower values in the subsets (calculated with ECFP fingerprints) No compound overlap with the previous edition (PS8 does not overlap with P7) Lipinski Rule of Five and Veber criteria-compliant compounds were selected Reagents, reactive or unstable molecules were excluded PAINS filter families A, B, and C were applied Lilly MedChem Rules compliance is guaranteed

- 2000 species of compounds related to liver cancer that can be used in anti-liver cancer drug development and pharmacological studies. - The target pathways include PI3K/Akt/mTOR, EGFR, FGFR, Met, etc.. - Some compounds are already approved or in clinical phase. - Detailed instructions, compound structures, target information, IC50 values, activity descriptions, etc. - Various detection techniques such as NMR, HPLC/LCMS to ensure correct structure and high purity of the product and reduce false positives.