Labelling

Our potent and selective hA1 Adenosin receptor fluorescent antagonist shows affinity and selectivity for hA1, (Ki =26.2 nM in radioligand binding assays). It allows to perform cell visualization in fluorescence microscopy, confocal microscopy and high content system experiments. It is potentially suitable for other fluorescence-based assays.

Our hCB2 cannabinoids receptor fluorescent ligand shows high affinity for hCB2 cannabinoids receptor and selectivity over hCB1 (Ki =75.9 nM for hCB2 receptor in radioligand binding assay). It is suitable for HTRF binding assays as a valid alternative to radioligand binding assays. It allows to perform cell visualization in fluorescence microscopy, confocal and high content system experiments. It is potentially suitable for other fluorescence-based assays.

This is a substrate for Immunofluorescence, enabling a highly sensitive detection of cellular surface antigen expression. A highly sensitive CLAMP method (quinone methide-based catalyzed signal amplification) can be applied to live/fixed cells or tissue sections. In this method, using β-galactosidase-labeled secondary antibody and newly developed fluorescent dye CLAMP F45, the cells expressing a specific cell surface protein are selectively and highly sensitively stained.

Streptavidin Agarose Ultra Performance™, 2 mL

Sulfo-Cy3-PEG2-TCO is a fluorophore featuring a sulfonate group and a TCO moiety. TCO is a click chemistry handle which readily reacts with tetrazine groups on a target molecule. Cy3 is a cyanine dye with excitation and emission maxima at 555 nm and 570 nm respectively. The sulfonate group on the Cy3 dye increases this compound’s solubility in water.

1-Pyrenebutyric acid N-hydroxysuccinimide ester is a pyrene labeled linker with an NHS ester. The 1-Pyrenebutyric acid is used in the surface functionalization of carbon nanotube and graphene, graphene oxide, reduced graphene oxide. A strong pi-pi stacking is formed between the pyrene and the aromatic rings on single wall and multi-walled carbon nanotubes.

Pyrenebutyricamide-PEG5-amine, TFA salt is a molecule featuring a polycyclic benzene framework known as pyrene ligated to a PEG-amine. The amine may participate in a variety of reactions such as coupling with carboxylic acids. Meanwhile, pyrene is a versatile material which may be derivatized to form fluorescent dyes or used in the surface functionalization of carbon nanotubes or graphene-derivatives to provide stability through pi-pi stacking between the pyrene and the aromatic rings of these compounds.

Coumarin 343 acid is a blue emitting fluorophore with a carboxylic acid handle.

Coumarin 343 acid is a blue emitting fluorophore with a NHS ester handle.