Lipids

Gamma-linolenic acid is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease.

trans-11-Eicosenoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

8(z)-eicosenoic acid

(Z)-Icos-11-enoic acid

cis-5-Eicosenoic acid

11(Z),14(Z)-Eicosadienoic acid is an uncommon, naturally occurring PUFA. It inhibits the binding of [3H]-LTB4 to pig neutrophil membranes with a Ki of 3 µM.

Eicosatrienoic Acid (20:3 Omega-3) is a rare polyunsaturated fatty acid of the Omega-3 series. In normal humans, it represents less than 0.25% of serum phospholipid fatty acids. However, it is one of the most active essential fatty acids when assayed for the inhibition of fatty acid elongation/desaturation reactions which convert dietary C-18 fatty acids to C-20 eicosanoid precursors.

Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (Omega-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein delta (C/EBPdelta). Eicosapentaenoic Acid activates RAS/ERK/C/EBPbeta pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation.

Docosapentaenoic acid is an Omega-3 fatty acid found in fish oils. It is a minor constituent of the total serum unsaturated fatty acids in humans, ranging from 0.1 to 1%, and increases on dietary supplementation.