PEG

Amino-Tri-(carboxyethoxymethyl)-methane is a branched molecule that is reactive towards carboxylic acids in the presence of HATU. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid is a heterotrifunctional PEG linker containing azide (N3), amine(NH2), and carboxylic acid(CO2H) moieties. The azide can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. An amine is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-(Azido-PEG3)-NH-PEG3-acid is an aqueous soluble PEG reagent with a terminal azide group and terminal carboxylic acid. the secondary amine NH group is reactive with NHS ester, The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The azide group can participate in Click Chemistry. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

t-Boc-N-amido-PEG1-NHS ester is a PEG linker containing NHS ester and Boc-protected amine moieties. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc group can be deprotected under mild acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

t-Boc-N-amido-PEG2-NHS ester is a PEG linker containing an NHS ester and a t-Boc protected amine group. The hydrophilic PEG spacer increases the solubility of compounds in aqueous media. The t-Boc group can be deprotected under mild acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a click chemistry reagent. The azide (N3) group participates in Click Chemistry reactions with alkynes, DBCO and BCN. The terminal carboxylic acid can react with primary amine groups. The Boc protection can be removed under acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Bis-PEG-TFP ester, MW 5,000 is an amine reactive PEG active ester. Similar to NHS-ester compound, it is used for PEGylation due to its reactivity with primary amine. However, TFP ester offers more stability (against hydrolysis) during conjugation resulting in higher coupling efficiency. Reagent grade, for research purpose.

PEG-bis-CH2CO2H, MW 5,000 can be used to modify N-terminus of protein/peptide and other amino molecule via amide bond formation in the presence of activator, such as HATU or EDC. Reagent grade, for research purpose.

HO-PEG-amine, MW 10,000 is a PEGylation reagent which contains hydroxyl and amine moieties. Amine is reactive with NHS esters or carboxylic acids in the presence of HATU or EDC. The hydroxyl group facilitates further derivatization producing different functional groups. Reagent grade, for research purpose.