PEG

TCO-PEG24-NHS Ester is a monodisperse PEG linker containing a TCO moiety and an NHS ester. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety. TCO enable click chemistry with tetrazine Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-PEG24-NHS ester is an anqueous water soluble, long PEG chain compound containing a methyltetrazine group. NHS ester can react with primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slightly basic pH to form covalent bonds. Methyltetrazine is reaactive with TCO via click chemistry. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-PEG3-NH-Boc is a click chemistry reagent attached with a Boc protecting group. The hydrophilic PEG spacer arm improves water solubility and is transferrable to the labeled molecule, reducing aggregation of labeled proteins stored in solution. The Boc protecting group can be removed under acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

m-PEG5-nitrile is a PEG linker containing a nitrile terminal group. The nitrile group can undergo hydrolysis, reduction and other reactions. The hydrophilic PEG spacer increases the solubility of compounds in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

TCO-OH is a TCO intermediate allowed for further derivatizion Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azido-PEG4-nitrile is a PEG linker which contains an azido group and a nitrile group. The azido group is commonly used in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN to produce triazole linkages. The nitrile group can undergo hydrolysis, reduction and other reactions. The hydrophilic PEG spacer increases the solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Hydroxy-PEG4-nitrile is a PEG linker which contains a hydroxyl group and a nitrile group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The nitrile group can undergo hydrolysis, reduction and other reactions. The hydrophilic PEG spacer increases the solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Fmoc-aminooxy-PEG12-NHS ester is a crosslinker molecule. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media. Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

(S, R, S)-AHPC-PEG8-NHS ester is PROTAC linker that incorporatess an E3 ligase ligand with a PEG4 spacer PEG4 arm increases the molecule's solubility. NHS ester group is very reactive with amine molecule. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.