PEG

Azido-PEG3-CH2CO2-NHS consist of azide and NHS ester moieties The azide(N3) group is reactive with alkynes, BCN and DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azido-PEG1-CH2CO2-NHS is a PEG linker containing azide and NHS ester moieties. The hydrophilic PEG spacer increases the water solubility of compounds in aqueous media. The azide group can react with alkynes, BCN and DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

m-PEG13-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases the water solubility of compounds in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Hydroxy-PEG4-methyl ester is a PEG linker containing hydroxyl and methyl ester moieties. The hydrophilic PEG spacer increases the water solubility of compounds in aqueous media. The hydroxyl group enables further derivatization or replacement with other functional groups. Methyl ester can be hydrolyzed under strong basic condition. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DOTA-(t-Butyl)3-PEG5-azide contains DOTA-(t-butyl) and azide moieties. The DOTA-(t-Butyl) is soluble in DMF and DCM. The t-Butyl groups can be removed under acidic conditions to produce free carboxylic acid. The azide group is commonly used in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN. The PEG chain increases the water solubility of compounds in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DOTA-PEG5-azide contains DOTA and azide moieties. DOTA is used as a chelating agent for cations. Azides are commonly used in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN to from triazole linkages. The PEG linker increases the water solubility of compounds in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

t-boc-N-amido-PEG8-azide is a monodisperse PEG linker. PEG8 spacer increases the solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry. The Boc group can be deprotected under mild acidic conditions to form the free amine. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

3-[[2-[(4-azidobenzoyl)amino]ethyl]dithio]propanoicacid contains an aryl azide, a cleavable disulfide bond, and a carboxylic acid. The aryl azide can be photo-activated with UV light (250 to 350 nm) for conjugation with biomolecules. The carboxylic acid can be reacted with amines in the presence of an activator to form an amide bond. The disulfide bond can be cleaved via reducing agents. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-PEG5-acid is an analog of DBCO-Acid with PEG linker and a DBCO group. DBCO group is a highly reactive cycloalkyne which is commonly used for copper-free Click Chemistry reactions. The hydrophilic PEG chain allows for increased water solubility of compounds in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.