PEG

TCO-PEG24-acid is a monodisperse, aqueous soluble PEG reagent with a TCO moiety. Carboxylic acid (CO2H) can react with primary amine groups in the presence of activators. TCO is very reactive with tetrazine-containing molecule. The inverse-electron demand Diels-Alder cycloaddition of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Biotin-PEG-biotin, MW 1,000 is a biotin molecule with strong binding with avidin/streptavidin and can be used for target detection and chemical labeling. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Bromoacetamido-PEG3-DOTA is a PEG linker containing a bromine moiety and a t-butyl protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The DOTA group can be ionized and is susceptible for chelating di- and trivalent cations. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

m-PEG5-azide is a PEG linker containing an azide moiety. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

t-Boc-Aminooxy-PEG12-t-butyl ester is a PEG linker containing a Boc-protected aminooxy group and a terminal carboxylic acid. The hydrophilic PEG spacer increases water solubility in aqueous media. The Boc-protected amine can be deprotected under mild acidic conditions. The t-butyl protected carboxyl group can be deprotected under acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

t-Boc-Aminooxy-PEG12-acid is a water soluble PEG reagent The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable bond. The Boc-protected amine can be deprotected under mild acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-NH-Boc is a click chemistry reagent with a DBCO group. DBCO can undergo copper-free Click Chemistry reactions with azides. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-PEG23-amine HCl salt is a monodisperse, click chemistry PEG linker containing a free amine and a methyltetrazine group. It is highly soluble in water. Amine (NH2) is reactive with carboxylic acid containing molecule in the presence of reagnet such as EDC or HATU. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene) Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

TCO-PEG3-amine is a click chemistry building block containing a TCO moiety and a free amine. Amine is very reactive with active NHS ester or with carboxylic acid in the presence of of activators suh as EDC. TCO moiety is very reactive with tetrazine ( 3rd generation click chemistry). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.