PEG

t-Boc-Aminooxy-PEG8-Ms is a crosslinking reagent containing a t-Boc-aminooxy group and a mesyl (Ms) group. The mesyl group is good leaving group. The protected amine can be deprotected under mild acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Ms-PEG8-t-butyl ester is a PEG linker with a mesyl group and a t-butyl protecting group. Mesyl is a good leaving group and can participate in substitution reactions. The t-butyl group can be removed under acidic condtions. The hydrophilic PEG linker increases the solubility properties of compounds in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

TCO-PEG12-TFP ester is a click chemistry PEG PFP ester. The hydrophilic PEG12 spacer increases water-solubility and decreases steric hindrance during ligation. It can be used to label amine-containing antibodies, proteins or peptide molecules with TCO moiety. The PFP ester is amine-reactive, stable compound. PFP esters are less susceptible toward hydrolysis compared to NHS esters. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

TCO-PEG8-TFP ester is a monodisperse crosslinker containing a TCO moiety and an PFP ester. The hydrophilic PEG8 arm increases water-solubility and decreases steric hindrance during ligation. This reagent can be used to label amine-containing antibodies, proteins and other macromolecules with TCO moiety. The PFP ester is amine-reactive, stable compound. PFP esters are less susceptible toward hydrolysis compared to NHS esters. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Bromo-PEG1-azide is a bifunctional PEG linker with a bromide (Br)group and an azide(N3) group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The bromide (Br) is a good leaving group for nucleophilic substitution reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

TCO-PEG8-acid is a very reactive click chemistry reagent. The terminal carboxylic acid (CO2H) can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable bond. TCO moiety is reactive with tetrazine-containing compounds to form a stable bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Propargyl-PEG3-triethoxysilane is consists of a triethoxysilane moiety and an alkyne group. Triethoxysilane is commonly used for surface modifications. The alkyne group can participate in Click Chemistry reactions with azide-bearing compounds or biomolecules; copper is used as a catalyst in the reaction. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-PEG7-NH-Boc is a click chemistry crosslinker containing methyltetrazine and a Boc protecting group. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene). The hydrophilic PEG spacer arm improves water solubility and is transferrable to the labeled molecule, reducing aggregation of labeled proteins stored in solution. The Boc protecting group can be removed under acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

t-Boc-Aminooxy-PEG5-amine compound contains a Boc-protected aminooxy group and an amino group. The amino group is reactive with carboxylic acids, activated NHS esters. The protected aminooxy can be deprotected under mild acidic conditions and then can react with an aldehyde or ketone group to form a stable oxime linkage. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.