PEG

Fmoc-N-amido-PEG-NHS ester, MW 2,000 is a PEGylation reagent containing a Fmoc protecting group and a terminal succinimidyl group. NHS ester is reactive with amine nucleophile very rapidly at pH 7-9. The hydrophilic PEG chain increases the water solubility properties of the compound. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. Reagent grade, for research purpose.

Fmoc-N-amido-PEG-Succinimidyl Valerate, MW 3,400 is an amine-protected PEG polymer with a succinimidyl group. The molecule can react with amine group of lysine or other amino molecule. The Fmoc group can be deprotected under basic condition to obtain the free amine for further conjugations. The PEG spacer is hydrophilic and therefore increases the water solubility properties of the compound. Reagent grade, for research purpose.

HO-PEG-amine, MW 20,000 is an amino PEGylation reagent which is reactive with NHS ester via formation of a stable amide bond. The hydroxyl group enables further derivatization or replacement with other reactive group. Reagent grade, for research purpose.

HO-PEG-CH2COOH, MW 10,000 is a -COOH PEG polymer. The hydroxyl group can be used to derivatize the compound. The terminal carboxylic acid can react with primary amines in the presence of activator, such as EDC or HATU, to form a stable amide linkage. Reagent grade, for research purpose.

HO-PEG-Mal, MW 10,000 is a water soluble thiol reactive PEG polymer. The hydroxyl group can be further derivatized. Reagent grade, for research purpose.

HO-PEG-Mal, MW 2,000 is a thiol reactive PEG polymer. The PEG is water soluble and hydroxyl moiety allows further modification with other reactive group. Reagent grade, for research purpose.

HO-PEG-valeric acid, MW 3,400 is a water soluble PEG polymer with a terminal carboxylic acid. The hydroxyl group can be further modified to derivatize the compound. The carboxylic acid can react with primary amines in the presence of activator, such as EDC or HATU, to form a stable amide bond. Reagent grade, for research purpose.

Mal-PEG-Succinimidyl Valerate, MW 3,400 is an amine reactive PEG polymer with a terminal maleimide which is reactive with thiol via thioether bond formation. Reagent grade, for research purpose.

Mal-PEG-Succinimidyl Valerate, MW 5,000 is a linear heterobifunctional polyPEG reagent. Maleimide reacts with thiol molecule at pH 6.5 to 7.5. The active ester group reacts with an amine to form a covalent amide bond. Reagent grade, for research purpose.