Cytokines & Chemokines

Recombinant Human MCP-2 (CCL8) (Legacy Tebubio ref. 167300-15). The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated Tcells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-2 is an 8.9 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Recombinant Human MCP-2 (CCL8) (Legacy Tebubio ref. 167300-15). The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated Tcells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-2 is an 8.9 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Recombinant Human PF-4 (CXCL4) (Legacy Tebubio ref. 167300-16). PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the alpha-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes, and has been shown to inhibit angiogenesis. Recombinant Human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.

Recombinant Human PF-4 (CXCL4) (Legacy Tebubio ref. 167300-16). PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the alpha-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes, and has been shown to inhibit angiogenesis. Recombinant Human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.

Recombinant Human MCP-3 (CCL7) (Legacy Tebubio ref. 167300-17). The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated Tcells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-3 is a 9.0 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Recombinant Human MCP-3 (CCL7) (Legacy Tebubio ref. 167300-17). The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated Tcells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-3 is a 9.0 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Recombinant Human Lymphotactin (XCL1) (Legacy Tebubio ref. 167300-20). Lymphotactin is the only known member of the C chemokine family, and signals through the receptor XCR1, formally known as GPR5. The spleen shows the highest level of lymphotactin compared to peripheral leukocytes, lung, colon and small intestine. Lymphotactin is chemotactic towards lymphocytes, but not towards monocytes or neutrophils. Recombinant Human Lymphotactin is a 10.0 kDa protein consisting of 92 amino acid residues.

Recombinant Human Lymphotactin (XCL1) (Legacy Tebubio ref. 167300-20). Lymphotactin is the only known member of the C chemokine family, and signals through the receptor XCR1, formally known as GPR5. The spleen shows the highest level of lymphotactin compared to peripheral leukocytes, lung, colon and small intestine. Lymphotactin is chemotactic towards lymphocytes, but not towards monocytes or neutrophils. Recombinant Human Lymphotactin is a 10.0 kDa protein consisting of 92 amino acid residues.

Recombinant Human Eotaxin (CCL11) (Legacy Tebubio ref. 167300-21). Eotaxin is a CC chemokine that signals through the CCR3 receptor. It is produced by IFN-gamma-stimulated endothelial cells and TNF-activated monocytes. Eotaxin selectively chemoattracts eosinophils and, along with Eotaxin-2 and Eotaxin-3, plays a key role in the regulation of eosinophil recruitment in the asthmatic lung and in allergic reactions. Recombinant Human Eotaxin is an 8.3 kDa protein containing 74 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.