Results for Peptides & Amino Acids ( 10737 )
- From: €98.00
PLP (139-151) peptide is a fragment of myelin proteolipid protein (PLP or lipophilin), from amino acid residue 139 to 151 (HCLGKWLGHPDKF – CAS 131334-43-5 ). Myelin proteolipid protein is the major myelin protein from the central nervous system. PLP (139-151) peptide is commonly used to induce experimental autoimmune encephalomyelitis (EAE) in SJL/J mice. The PLP (139-151) peptide C140S is mutant of the wild-type version where the cystein is replaced by a serine to make the peptide more stable without impacting its antigenic activity.
- From: €146.00
CEF (cytomegalovirus, Epstein-Barr virus, and influenza virus) control peptide pool for immune cell activation. CEF32 peptide pool is a positive control for CD8 cell activation. The CEF Control Peptide Pool (HLA Class I Control) is a mixture of 32 peptides derived from the human Cytomegalovirus (CMV), Epstein-Barr Virus (EBV) and Influenza Virus (Flu). The CEF Control Peptide Pool (HLA Class I Control) contains a defined HLA class I-restricted T cell epitopes from these three viruses. CEF peptide pool stimulates CD8+ T cells and allows to ensure that PBMC (peripheral blood mononuclear cells) are still functionnal after storage, freezing/thawing by verifying secretion of cytokines from antigen-specific T cells.
- From: €171.00
Apelin-36 (human) (CAS: 252642-12-9) Apelin GPCR-Receptor The Apelin receptor, also known as APJ, APLNR, and AGTRL1, is a member of the class A family of G protein-coupled receptors (GPCRs). It has been identified in various species, including mouse, rat, cow, rhesus macaque, Xenopus laevis, and Danio rerio, and it shares structural similarities with the angiotensin II type l receptor (AT1). However, despite a 54% homology in transmembrane regions with AT1, it does not bind angiotensin II. Initially designated as an "orphan" GPCR, due to the absence of a known ligand, O'Dowd & al. named it APJ in 19935. Comprising 380 amino acid residues, APJ features the characteristic 7-transmembrane domain structure, typical of a class A GPCR. Nowadays, it is known that APLNR depicts physiological roles, including regulation of cardiovascular function, fluid homeostasis, the adipoinsular axis, gastrointestinal and immunomodulatory functions. Apelin isoforms Apelin (APLN) endogenous APJ lig