Results for Peptides & Amino Acids ( 10747 )
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Glucagon (1-29) – Human, Porcine (CAS: 16941-32-5) SB-PEPTIDE offers glucagon 1-29 peptide HSQGTFTSDYSKYLDSRRAQDFVQWLMNT for research on diabetes, obesity, and non-alcoholic fatty liver disease (NAFLD). G-Protein Coupled Receptor Glucagon operates through the GPCR signaling pathway, which plays a pivotal role in cellular communication. This type of receptors are known as seven-transmembrane domain receptors, which possess a unique structure that enables them to detect external molecules and activate cellular responses. Their vital association with G proteins fuels a cascade of events, initiating a cellular symphony, orchestrated by two principal signal transduction pathways: the cAMP signal pathway and the phosphatidylinositol signal pathway. Glucagon class B GPCR receptor - Glucagon peptide CAS: 16941-32-5 Glucagon class B GPCR 3D structure Glucagon receptor/class B GPCR GPCR superfamily is organized into three main classes, among which the secretin receptor family
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Apolipoprotein E fragment (133-149) – COG133: acetyl-LRVRLASHLRKLRKRLL-NH2 (CAS : 514200-66-9) SB-PEPTIDE offers Apolipoprotein E (ApoE) mimetic peptide COG133 – LRVRLASHLRKLRKRLL – which competes with the ApoE holoprotein for binding the low density lipoprotein (LDL) receptor. Apolipoprotein E (ApoE): A key player in lipid transport and beyond Apolipoprotein E (apoE) is a low-density lipoprotein (LDL) receptor ligand that belongs to the family of fat-binding proteins, known as apolipoproteins. While the liver and macrophages primarily produce ApoE in peripheral tissues to mediate cholesterol metabolism, in the central nervous system (CNS), astrocytes take the lead in producing ApoE. ApoE plays a vital role in lipid transport, facilitating the movement of lipids such as fats, cholesterol, and fat-soluble vitamins between organs via plasma and interstitial fluids. In the central CNS, it serves as a crucial cholesterol carrier, promoting neuron survival, sprouting, and exhibiting