Peptides & Amino Acids

Haemagglutinin (HA) peptide YPYDVPDYA – HA Tag SB-PEPTIDE offers Human influenza hemagglutinin (HA) tag YPYDVPDYA, which is a well characterized 9 amino acids synthetic peptide deriving from an epitope of the original influenza hemagglutinin protein. Haemagglutinin surface fusion glycoprotein for viral entry Haemagglutinin (HA) (UniProt : P03437) is an envelope protein present in the viral membrane of influenza viruses. HA forms a trimer containing structurally distinct regions and an intact HA0 polypeptide composed of two subunits, called HA1 and HA2, connected by one disulfide bridge. Haemagglutinin (HA) 3D structure. HA tag SB-PEPTIDE_CAS: 92000-76-5 To initiate their fusion with their cellular hosts, influenza viruses first bind to sialic acids at the surface of respiratory epithelial cells. Following this interaction, they will enter the cell via endocytosis. Endosomal uptake of influenza virus - HA tag SB-PEPTIDE_CAS: 92000-76-5 Due to proton pumps on t

Huwentoxin IV (HwTx-IV) is a neurotoxin that was originally isolated from Haplopelma schmidti (Chinese bird spider). This lethal neurotoxin acts selectively on tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels, with an IC50 of 30 nM in rat DRG neurons. It preferentially inhibits neuronal voltage-gated sodium channel subtype hNav1.7 (SCN9A, IC50 is 26 nM), rNav1.2 (SCN2A, IC50 is 150 nM), and rNav1.3 (SCN3A, IC50 is 338 nM), compared with muscle subtypes rNav1.4 (SCN4A) and hNav1.5 (SCN5A) (IC50 is > 10 µM). Huwentoxin IV inhibits the activation of sodium channels by trapping the voltage sensor of domain II of the site 4 in the inward, closed configuration. Cy5-Huwentoxin IV is a fluorescently tagged version of Huwentoxin IV.

Cy5-ProTx-II is a fluorescently labeled ProTx-II, a famous Nav1.7 blocker. The wild type ProTx-II blocks Nav1.7 with an IC50 value of around 300 pM, Nav1.2, Nav1.5 and Nav1.6 with IC50 values of 41 nM, 79 nM and 26 nM respectively. The Cy5-ProTx-II version developed by Smartox has potent Nav1.7 blocking activity. It was shown to fully block Nav1.7 at 100 nM concentration.

Recombinant human AGR2 protein derived from E.coli

Recombinant SARS-CoV-2 Spike Protein, S1 Subunit derived from E.coli

Recombinant SARS-CoV-2 Spike Protein, S2 Subunit derived from E.coli

Recombinant human HCG-beta (CGB3) with an N-terminal His-tag, derived from the transfected human HEK293 cells.

Recombinant human HCG-beta (CGB3) with an N-terminal His-tag, derived from the transfected human HEK293 cells.