Lentivirus

LV-EF1α-NLS-mCherry-Puro is a pre-made lentivirus which expresses mCherry fused with SV40 nuclear localization sequence (NLS) under the EF1α promoter with co-expression of puromycin selection in a IRES cassette. Ready to use format.

PD-L1 Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles ready to transduce nearly all types of mammalian cells, including primary and non-dividing cells. These viruses contain human PD-L1 (programmed death ligand 1) (NM_014143.4) driven by an EF1a promoter and a geneticin selection marker.

MAGE-A1-Specific TCR Lentivirus (Clone 1367) are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles ready to transduce nearly all types of mammalian cells, including primary and non-dividing cells. These viruses transduce cells with a TCR (T cell receptor) (clone 1367) that specifically recognizes the human antigen MAGE-A1 (Melanoma-associated antigen 1), and in which the TCR α chain and β chain are linked by P2A. The lentiviruses also transduce a puromycin selection marker. Mouse TCR constant regions were used in this construct to boost expression.

MAGE-A1-Specific TCR Lentivirus (Clone 1367) are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles ready to transduce nearly all types of mammalian cells, including primary and non-dividing cells. These viruses transduce cells with a TCR (T cell receptor) (clone 1367) that specifically recognizes the human antigen MAGE-A1 (Melanoma-associated antigen 1), and in which the TCR α chain and β chain are linked by P2A. The lentiviruses also transduce a puromycin selection marker. Mouse TCR constant regions were used in this construct to boost expression.

MAGE-A4-Specific TCR Lentivirus are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles ready to transduce nearly all types of mammalian cells, including primary and non-dividing cells. These viruses transduce cells with a TCR (T cell receptor) that specifically recognizes the human antigen MAGE-A4 (Melanoma-associated antigen 4) peptide 230-239 (GVYDGREHTV), and in which the TCR α chain and β chain are linked by P2A. The lentiviruses also transduce a puromycin selection marker.

MAGE-A4-Specific TCR Lentivirus are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles ready to transduce nearly all types of mammalian cells, including primary and non-dividing cells. These viruses transduce cells with a TCR (T cell receptor) that specifically recognizes the human antigen MAGE-A4 (Melanoma-associated antigen 4) peptide 230-239 (GVYDGREHTV), and in which the TCR α chain and β chain are linked by P2A. The lentiviruses also transduce a puromycin selection marker.

KRAS G12D-Specific TCR Lentivirus (Clone 9c) are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles ready to transduce nearly all types of mammalian cells, including primary and non-dividing cells. These viruses transduce cells with a TCR (T cell receptor) (clone 9c) that specifically recognizes the human antigen KRAS (Kirsten rat sarcoma virus) G12D, and in which the TCR α chain and β chain are linked by P2A. The lentiviruses also transduce a puromycin selection marker. Mouse TCR constant regions were used in this construct to boost expression.

KRAS G12D-Specific TCR Lentivirus (Clone 9c) are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles ready to transduce nearly all types of mammalian cells, including primary and non-dividing cells. These viruses transduce cells with a TCR (T cell receptor) (clone 9c) that specifically recognizes the human antigen KRAS (Kirsten rat sarcoma virus) G12D, and in which the TCR α chain and β chain are linked by P2A. The lentiviruses also transduce a puromycin selection marker. Mouse TCR constant regions were used in this construct to boost expression.

KRAS G12D-Specific TCR Lentivirus (Clone 10) are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles ready to transduce nearly all types of mammalian cells, including primary and non-dividing cells. These viruses transduce cells with a TCR (T cell receptor) (clone 10) that specifically recognizes the human antigen KRAS (Kirsten rat sarcoma virus) G12D, and in which the TCR α chain and β chain are linked by P2A. The lentiviruses also transduce a puromycin selection marker. Mouse TCR constant regions were used in this construct to boost expression.