Lipids

A synthetic phosphatidylinositol (3)-phospate [PI(3)P] analog in which the 3-phosphate has been rendered metabolically stable as a phosphothionate. P-3S18 has been shown to bind to the FYVE domain and is a substrate for the 5-kinase PIKfyve. Powered by Bioz See more details on Bioz

PtdIns(3 4 5)P3 3-phosphothioate diC8 (3S-PtdIns(3 4 5)P3 diC8) is a water-soluble synthetic PI(3 4 5)P3 analog in which the 3-phosphate has been rendered metabolically stable as a phosphorothioate. P-3S908 shows 90% inhibition of PTEN at 0.4µM. Powered by Bioz See more details on Bioz

PtdIns(3 4 5)P3 3-phosphothioate diC16 (3S-PtdIns(3 4 5)P3 diC16) is a synthetic PI(3 4 5)P3 analog in which the 3-phosphate has been rendered metabolically stable as a phosphorothioate. P-3S916 increases sodium transport across monolayers of cells A6 through activation of GLUT4.

Glycerophosphoinositol 4-phosphate (GroPI(4)P) is a synthetic purified PI(4)P without acyl chains at the 1- and 2-positions of the glycerol.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4 5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex.Bulk discounts available please email echelon@echelon-inc.com for information.

Phosphatidylinositol 4-phosphate diC4 (PI(4)P diC4) is a synthetic purified dibutanoyl PI(4)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4 5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex.Product Keywords: D-myo-Phosphatidylinositol 4-phosphate Dibutanoyl Phosphatidylinositol 4-phosphate PtdIns(4)P C4 PI(4)P C4 or PI4PBulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz1) Guo J. M. R. Wenk et al. (2003). "Phosphatidylinositol 4-kinase type IIalpha is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles." Proc Natl Acad Sci U S A 100(7): 3995-4000.2) Schoebel S. W. Blankenfeldt et al. (2010)

Phosphatidylinositol 4-phosphate diC8 (PI(4)P diC8) is a synthetic purified dioctanoyl PI(4)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4 5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex.Alternate names: D-myo-Phosphatidylinositol 4-phosphate Dioctanoyl Phosphatidylinositol 4-phosphate PtdIns(4)P C8   PI(4)P C8 8:0/8:0 PI(4)PBulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz1) Chang J. D. S. J. Field et al. (2004). "Identification and characterization of a phosphoinositide phosphate kinase homolog." J Biol Chem 279(12): 11672-9.2) Redfern D. A. and A. Gericke (2004). "Domain formation in phosphatidylinositol monophosphate/phosph

Phosphatidylinositol 4-phosphate diC8 (PI(4)P diC8) (ammonium salt) is a synthetic purified dioctanoyl PI(4)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate is the biosynthetic precursor to PI(4 5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex.Featured in PublicationsJournal of Biological Chemistry Nov 2005Alternate names: Dioctanoyl Phosphatidylinositol 4-phosphate PtdIns(4)P C8   PI(4)P C8 8:0/8:0 PI(4)PBulk discounts available please email echelon@echelon-inc.com for details.

Phosphatidylinositol 4-phosphate diC16 (PI(4)P diC16) is a synthetic purified dipalmitoyl PI(4)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4 5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex.Product Keywords: D-myo-Phosphatidylinositol 4-phosphate Dipalmitoyl Phosphatidylinositol 4-phosphate PtdIns(4)P C16 PI(4)P C16 or PI4PBulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz1) Barylko B. S. H. Gerber et al. (2001). "A Novel Family of Phosphatidylinositol 4-Kinases Conserved from Yeast to Humans." J Biol Chem 276(11): 7705-7708.2) Thole J. M. J. E. Vermeer et al. (2008). "Root hair defective4 encodes a phosphatidylinositol-4-phos

Glycerophosphoinositol 4 5-diphosphate (GroPI(4 5)P2) is a synthetic purified PI(4 5)P2 without acyl chains at the 1- and 2-positions of the glycerol.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4 5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues and is also a substrate for class I phosphoinositide 3-kinase (PI3-K).Bulk discounts available please email echelon@echelon-inc.com for information.