Lipids & Polymers

Phosphatidylinositol 4 5-bisphosphate diC8 (PI(4 5)P2 diC8) is a synthetic purified dioctanoyl PI(4 5)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4 5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues and is also a substrate for class I phosphoinositide 3-kinase (PI3-K).Alternate Names: D-myo-Phosphatidylinositol 4 5-bisphosphate Dioctanoyl Phosphatidylinositol 4 5-bisphosphate PtdIns(4 5)P2 C8 PI(4 5)P2 C8 or PIP2Bulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz1) Jenco J. M. A. Rawlingson et al. (1998). "Regulation of phospholipase D2: selective inhibition of mammalian phospholipase

Lipid coated beads are designed for use in protein pull-down experiments. Use to test for lipid binding of purified protein proteins in cell lysate or binding of radiolabeled in vitro translation products.Control Beads are blocked agarose beads for use as a negative control with Lipid Coated Beads.Storage4 °C - do not freeze Powered by Bioz See more details on Bioz

Lipid coated beads are designed for use in protein pull-down experiments. Use to test for lipid binding of purified protein proteins in cell lysate or binding of radiolabeled in vitro translation products.Phosphatidic Acid Beads are composed of agarose with 10 nanomoles of bound phosphatidic acid (PA) per 1ml of beads enough for several protein binding experiments. Each 1 mL order of Phosphatidic Acid Beads includes a small amount of control beads. Larger quantities of Control Beads are also available for purchase.Storage4 °C - do not freeze Powered by Bioz See more details on Bioz

This product contains Concanavalin A (ConA) conjugated to paramagnetic microspheres. ConA is a lectin (carbohydrate-binding protein) that binds specifically to mannosyl- and glucosyl-containing extracellular glycoproteins. The ConA magnetic beads are therefore useful to immobilize cells or nuclei presenting these glycans in their extracellular matrices.

Thiol-PEG4-acid is a PEG linker containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-PEG4-amine is an aqueous soluble PEGylation reagent containing a free amine and a methyltetrazine group. Methyl group improves the stability and hydrophilic PEG spacer increases water-solubility. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-mPEG, MW 5,000 is a click chemistry PEG polymer which can react with azides via a copper-free click chemistry to form a stable triazole linkage. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Sulfo DBCO-Amine can be used to derivatize carboxyl-containing molecules or activated esters (e.g. The NHS ester) with DBCO moiety through a stable amide bond. The low mass weight will add minimal spacer to modified molecules and the hydrophilic sulfonated spacer arm will greatly improve water solubility of DBCO derivatized molecules. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azido-PEG24-NHS ester is a monodisperse, high purity PEG linker. The azide group enables Click Chemistry. The NHS ester can be used to label the primary amines (-NH2) of proteins, oligonucleotides, and other amine-containing biomolecules. The hydrophilic PEG spacer adds to the water solubility of this reagent. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.