Lipids

PC/PS Lipid Microparticles contain attached phosphatidylcholine and phosphatidylserine with the phospholipid headgroups exposed and available for biological interactions. Phosphatidylserine (PS) is an anionic intracellular phospholipid component of the cell membrane and is involved in cell signaling including apoptosis. Phosphatidylcholine (PC) is primarily an extracellular phospholipid component of cell membranes and is a key structural lipid.Technicial Notes1. Total lipid concentration is approximately 1 μmol per 1 mg particles at a PC to PS ratio of 75:20.2. Trace amounts of a fluorescent lipid are embedded in the particles. The fluor has maximal excitation/emission at approximately 460/540 nm.3. Particle size is 3 µm.Storage4 °C - do not freezeDocumentsTechnical Data Sheet

PS Lipid Microparticles contain attached phosphatidylserine with the phospholipid headgroups exposed and available for biological interactions. Phosphatidylserine (PS) is an anionic intracellular phospholipid component of the cell membrane and is involved in cell signaling including apoptosis.Technicial Notes1. Total lipid concentration is approximately 1 μmol per 1 mg particles.2. Trace amounts of a fluorescent lipid are embedded in the particles. The fluor has maximal excitation/emission at approximately 460/540 nm.3. Particle size is 3 µm.Storage4 °C - do not freezeDocumentsTechnical Data Sheet 

PtdIns(4 5)P2 a-fluorophosphonate diC16 (ms-PtdIns(4 5)P2 diC16) is a synthetic PI(4 5)P2 analog in which the phosphodiester bond has been rendered metabolically stable via the α-fluorophosphonate. Powered by Bioz See more details on Bioz

Flow PIPs: Multiplex Lipid Beads are microparticles with attached lipids that can be used to determine and study lipid-protein interactions.Each pack of Flow PIPs: Multiplex Lipid Beads contain two mixes of assay particles. Each bead mix Mix A & Mix B contains six separately coated beads that vary in both the coating lipid and the fluorescence intensity of the bead allowing the user to determine if their protein of interest binds with one or more of the bound lipids in a multiplex cytometric format.Storage: 2-8 °C. Product is temperature and light sensitive. Do not freeze.Publications Powered by Bioz See more details on Bioz1. Zhang J Dubey P Padarti A Zhang A Patel R Patel V et al. Novel functions of CCM1 delimit the relationship of PTB/PH domains. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 2017;1865(10):1274-86.DocumentsTechnical Data Sheet

PtdIns(4 5)P2 a-fluorovinylphosphate diC8 is a water soluble synthetic PI(4 5)P2 analog in which the phosphodiester bond has been rendered metabolically stable via the α-fluorovinylphosphonate. P-FV4508 restores the TRPM4 ion channel current at similar concentrations as diC8-PI(4 5)P2.Featured in PublicationsJ. Am. Chem. Soc. 2006 Powered by Bioz See more details on Bioz

The PIP PACK is a bundle of lipid-protein interaction tests controls and a wash case.The pack contains: 5 PIP Strips and 2 Membrane Lipid Strips to identify binding 2 PIP Arrays to quantify binding affinity 2 vials of PI(4 5)P2 specific binding protein (G-4501) for use as positive controls 1 wash caseSphingo Strips (S-6000) and Sphingo Arrays (S-6001) can be substituted in the PIP Pack. Powered by Bioz See more details on Bioz

Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1 3-bisphosphate (Ins(1 3)P2) is an intermediate in the inositol phosphate pathway being produced by dephosphorylation of Ins (1 3 4)P3 by type II inositol 1 3 4 trisphosphate 4-phosphatase.Bulk discounts available please email echelon@echelon-inc.com for information.

Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1 4-bisphosphate (Ins(1 4)P2) is an intermediate in the inositol phosphate pathway. It is produced by dephosphorylation of Ins(1 4 5)P3 by a 5-phosphatase thus terminating IP3 signaling. Ins(1 4)P2 is also a substrate for inositol 1-phosphatase. Powered by Bioz See more details on BiozReferences"Phosphatidylinositol and inositol phosphate metabolism." J. Cell Sci. 2001 114 2207-8.Keywords: D-myo-Inositol 1 4-bisphosphate Ins(1 4)P2 or I(1 4)P2Bulk discounts available please email echelon@echelon-inc.com for information.

Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1 5-bisphosphate (Ins(1 5)P2) is not an intermediate in the inositol phosphate pathway but corresponds to the PtdIns(5)P headgroup.Storage-20 °C Powered by Bioz See more details on BiozReferences"Phosphatidylinositol and inositol phosphate metabolism." J. Cell Sci. 2001 114 2207-8.Keywords: D-myo-Inositol 1 5-bisphosphate Ins(1 5)P2 or I(1 5)P2Bulk discounts available please email echelon@echelon-inc.com for information.