Lipids

Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1 2 6-trisphosphate (Ins(1 2 6)P3) or trinositol is an analog of Ins(1 4 5)P3 which inhibits inflammatory reactions inhibits edema formation in skin burns inhibits vasoconstriction by neropeptide Y (NPY) and treats acute nerve function abnormalities in diabetes.Bulk discounts available please email echelon@echelon-inc.com for information.

Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1 3 4-trisphosphate (Ins(1 3 4)P3) is an intermediate in the inositol phosphate pathway. Ins(1 3 4)P3 inhibits Ins(3 4 5 6)P4 1-kinase which regulates Ins(3 4 5 6)P4 levels. Ins(3 4 5 6)P4 in turn is responsible for inhibiting calcium-activated chloride channels. Ins(1 3 4)P3 is produced by dephosphorylation of Ins(1 3 4 5)P4 by a 5-phosphatase. Ins(1 3 4)P3 is a substrate for phosphatases yielding Ins(1 3)P2 and Ins(3 4)P2. Powered by Bioz See more details on BiozReferences"Phosphatidylinositol and inositol phosphate metabolism." J. Cell Sci. 2001 114 2207-8.Keywords: D-myo-Inositol 1 3 4-trisphosphate Ins(1 3 4)P3 or I(1 3 4)P3Bulk discounts available please email echelon@echelon-inc.com for information.

Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1 3 5-trisphosphate (Ins(1 3 5)P3) is not an intermediate in the inositol phosphate pathway but corresponds to the PtdIns(3 5)P2 headgroup. Powered by Bioz See more details on BiozReferences"Phosphatidylinositol and inositol phosphate metabolism." J. Cell Sci. 2001 114 2207-8.Keywords: D-myo-Inositol 1 3 5-trisphosphate Ins(1 3 5)P3 or I(1 3 5)P3Bulk discounts available please email echelon@echelon-inc.com for information.

Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1 4 5-trisphosphate (Ins(1 4 5)P3) aka IP3 is a second messenger produced by phospholipase C catalyzed hydrolysis of phosphatidylinositol 4 5-bisphosphate (PIP2). IP3 binds to the IP3-receptor on the endoplasmic reticulum causing calcium to be released through the opening of a tetrameric ion channel. IP3 is rapidly metabolized by a specific series of inositol phosphatases and kinases. Powered by Bioz See more details on BiozReferences"Phosphatidylinositol and inositol phosphate metabolism." J. Cell Sci. 2001 114 2207-8.Keywords: D-myo-Inositol 1 4 5-trisphosphate Ins(1 4 5)P3 I(1 4 5)P3 or IP3Bulk discounts available please email echelon@echelon-inc.com for information.

Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1 3 4 5-tetrakisphosphate (Ins(1 3 4 5)P4) aka IP4 is produced from Ins(1 4 5)P3 in stimulated cells by IP3 3-kinase (Itpkb). IP4 acts in conjunction with IP3 to mobilize intracellular calcium. In addition IP4 has roles in T cell precursor development and responsiveness and thymocyte reactivity to antigens. Powered by Bioz See more details on BiozReferences"Phosphatidylinositol and inositol phosphate metabolism." J. Cell Sci. 2001 114 2207-8.Keywords: D-myo-Inositol 1 3 4 5-tetrakisphosphate Ins(1 3 4 5)P4 I(1 3 4 5)P4 InsP4 or IP4Bulk discounts available please email echelon@echelon-inc.com for information.

Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1 3 4 6-tetrakissphosphate (Ins(1 3 4 6)P4) is an intermediate in the synthesis of InsP6 (phytic acid) being phosphorylated by Ins(1 3 4 6)P4 5-kinase to Ins(1 3 4 5 6)P5. It is formed from Ins(1 3 4)P3 by Ins(1 3 4)P3 5 6-kinase.References"Phosphatidylinositol and inositol phosphate metabolism." J. Cell Sci. 2001 114 2207-8.Keywords: D-myo-Inositol 1 3 4 6-tetrakisphosphate Ins(1 3 4 6)P4 or I(1 3 4 6)P4Bulk discounts available please email echelon@echelon-inc.com for information.

Inositol phosphates are important signaling molecules involved in numerous cellular functions. This Inositol 1 3 4 5-tetrakisphosphate (Ins(1 3 4 5)P4) analog is labeled with biotin through a three-carbon linker at the 1-position on the inositol ring.Keywords: D-myo-Inositol 1 3 4 5-tetrakisphosphate biotin biotin-Ins(1 3 4 5)P4 biotin-I(1 3 4 5)P4 or biotin-IP4Bulk discounts available please email echelon@echelon-inc.com for information.

Inositol phosphates are important signaling molecules involved in numerous cellular functions. This Inositol 1 4 5-trisphosphate (Ins(1 4 5)P3) analog is labeled with biotin through a three-carbon linker at the 1-position on the inositol ring. Powered by Bioz See more details on BiozKeywords: D-myo-Inositol 1 4 5-trisphosphate biotin biotin-Ins(1 4 5)P3 biotin-I(1 4 5)P3 or biotin-IP3Bulk discounts available please email echelon@echelon-inc.com for information.

Lipid coated beads are designed for use in protein pull-down experiments. Use to test for lipid binding of purified protein proteins in cell lysate or binding of radiolabeled in vitro translation products.Ins(1 3 4 5)P4 Beads are composed of agarose with 10 nanomoles of bound Ins(1 3 4 5)P4 per mL of beads enough for several protein binding experiments. Each 1 mL order of Ins(1 3 4 5)P4 Beads includes a small amount of control beads. Larger quantities of Control Beads are also available for purchase.<Storage4 °C - do not freeze