Lipids

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7-[(2-Hydroxyethyl)[8-(nonyloxy)-8-oxooctyl]amino]heptyl 2-octyldecanoate, analog of ALC-0315, is a ionizable, physiological pH cationic synthetic lipid that is used with other lipids to form lipid nanoparticles(LNP) for drug delivery. Reagent grade, for research use only.

1,1'-[2-(Hydroxymethyl)-1,3-propanediyl] dilinoleate is a lipid molecule featuring two linoleic acids and a primary alcohol. Compounds such as this may be used as intermediates in building lipids for use in lipid nanoparticles.

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nonyl 8-bromooctanoate is a chemical reagent featuring a bromide linked to a larger ester chain consisting of a C8 ester coupled to a C9 chain. Bromide is easily displaced by nucleophiles in substitution reactions. Compounds such as this may be used as intermediates in building lipids for use in lipid nanoparticles.

DSPE-Alkyne is a phospholipid compound with two 18-carbon lipid tails and a phosphate head joined by a glycerol molecule. The molecule can self-assemble in water to form lipid bilayer with hydrophobic tails facing the inner area an d hydrophilic head facing outward interacting with water. The compound can be used to prepare nanoparticles or liposomes for drug nanocarrier to deliver therapeutics, such as mRNA/DNA vaccine. The alkyne group enables click reaction with azido molecule in the presence of Cu catalyst. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DSPE-Biotin has strong binding with avidin or streptavidin for protein labelling or purification. The compound has phospholipid group with a hydrophilic phosphate connected to two fatty acids by a glycerol molecule. In water, the molecule can orient itself into lipid bilayer and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DSPE-glutaric acid is a phospholipid compound with two 18-carbon lipid tails and a phosphate joined by a glycerol molecule. The molecule can self-assemble in water to form lipid bilayer with hydrophobic tails facing the inner area an d hydrophilic head facing outward interacting with water. The compound can be used to prepare nanoparticles or liposomes for drug nanocarrier to deliver therapeutics, such as mRNA/DNA vaccine. The carboxylic acid moiety can be used for bioconjugation with amine in the presence of activating agent, such as HATU or EDC. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DSPE-SPDP is a phospholipid molecule which can orient itself to form lipid bilayer in water. The hydrophobic tails will face inner part while the hydrophilic head faces outward and interacts with water. The SPDP moiety is reactive with thiol molecule to form a disulfide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.