Lipids

N-Succinimidyl palmitate is an intermidate for synthesis of lipid molecules. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Palmitic acid-PEG4-acid is a saturated long-chain fatty acid with a 16-carbon backbone and a PEG likner connected to a terminal carboxylic acid group. The acid group can derivatize amine-containing molecules in the presence of activators such as EDC or HATU. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

14:0 DAP, 1,2-dimyristoyl-3-dimethylammonium-propane, is a cationic lipid that can be used to formulate lipid nanoparticles (LNPs). 18:0 DAP also serves as a pH-sensitive transfection reagent. Reagent grade, for research use only.

DORI, N-(2-hydroxyethyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium bromide, is an ionizable lipid with lower cytotoxicity and high transfection efficiency. Reagent grade, for research use only.

DOBAQ, N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium, is a cationic lipids with a quaternary amine and unsaturated hydrocarbon chains. DOBAQ also serves as a pH-sensitive transfection reagent. Reagent grade, for research use only.

16:0 DAP, 1,2-dipalmitoyl-3-dimethylammonium-propane, is a cationic lipid that can be used to formulate lipid nanoparticles (LNPs). 18:0 DAP also serves as a pH-sensitive transfection reagent. Reagent grade, for research use only.

8-bromooctyl 2-hexyldecanoate is an intermidate for synthesis of lipid molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Palmitic acid-PEG4-NHS ester is a saturated long-chain fatty acid with a 16-carbon backbone and a PEG likner connected to a terminal NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

6-(3-hydroxypropylamino)hexyl 2-hexyldecanoate is an amino ionizable lipid which can be used to make ALC-0315. The ethanolamine lipid head enhances encapsulation of mRNA. The lipid has identical ester bonds located adjacent to C6 relative to the amine nitrogen. The introduction of ester linkages can improve the clearance of the lipid in the liver. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.