Lipids

DODAC is a cationic lipid with a pair of unsaturated tails. This complex can serve as a well-defined intermediate in the preparation of DNA-lipid particles (DLPs) with many potential applications for delivery of polynucleotides in vitro and in vivo. Reagent grade, for research use only.

(2,2-dimethyl-1,3-dioxan-5-yl)methyl 6-bromohexanoate is a small molecule with an acetonide protection group and a terminal bromide group. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. Acetonide protection can be removed by hydrolysis of the ketal using dilute aqueous acid. Reagent grade, for research purpose.

nonyl 10-bromodecanoate is an intermidate for synthesis of lipid molecules. Reagent grade, for research purpose.

1,1'-[2-[( 6-bromohexanoate)methyl]-1,3-propanediyl] dipentadecan-7-yl adipate has a terminal bromide group and two 4,4-bis(octyloxy)butanoic acid tails. This compound can be useful for the building or modification of lipid nanoparticles. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. Reagent grade, for research purpose.

1,2-Di-O-tetradecyl-rac-glycerol is a hydrophobic compound that has been found to occure naturally in the body. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. It has been shown to inhibit folic acid metabolism, and can be used as an immunoregulator in vitro. Reagent grade, for research purpose.

(Z)-non-2-enyl 6-bromohexanoate, also known as D-Desthiobiotin, is an analogue of Biotin and a protein cross-linking agent. (Z)-non-2-enyl 6-bromohexanoate binds less tightly to biotin-binding proteins such as Avidin and is easily displaced by Biotin. It is used in the preparation of agarose matrices for affinity-based isolation of streptavidin-fluorophore conjugates. Reagent grade, for research purpose.

N-Hydroxysuccinimide Conjugated Ester derivative of Arachidic Acid (A764990), a saturated fatty acid and a minor constituent of peanut oil, coconut oil and corn oil.

Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signaling and inflammation.

Arachidonic acid methyl ester is an esterified form of arachidonic acid. It is commonly used as a reference standard for the quantification of arachidonic acid in biological samples and as a source of exogenous arachidonic acid in cells and in vivo.