PEG

m-PEG4-Hydrazide is a PEG-based linker for PROTACs, joining two essential ligands crucial for PROTAC molecule formation, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

BCN-PEG3-VC-PFP ester, a three-unit PEG ADC linker, is cleavable and commonly used in the synthesis of antibody-drug conjugates (ADCs) [1].

DBCO-PEG4-Desthiobiotin is a polyethylene glycol (PEG) derivative utilized as a linker for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

DBCO-SS-PEG4-Biotin, a cleavable, mid-functional ADC linker with a 4-unit PEG moiety, is used in the synthesis of antibody-drug conjugates (ADCs)[1].

N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5 is a polyethylene glycol (PEG)-derived PROTAC linker, used in the synthesis of PROTACs [1].

bis-Fluorescein-PEG8 is a fluorescein dye with excitation/emmission maximum 494/517 nm. Reagent grade, for research purpose.

Fluorescein-PEG8-NHS ester is a hydrophilic fluorophore containing a NHS ester group and a hydrophilic PEG spacer arm. The NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond. The hydrophilic PEG spacer arm increases water solubility and conjugation efficiency

PC Azido-PEG23-NHS carbonate ester functions features an amine-reactive NHS ester connected to a terminal azide via a photocleavable linker and PEG linker. This structure allows for efficient photorelease of linked molecules, typically achieving over 90% cleavage in 5-25 minutes using a near-UV lamp. The azido can participate in copper-catalyzed Click Chemistry reactions with alkynes, DBCO, and BCN. The NHS labels the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-bearing molecules. Reagent grade, for research purpose.

PC Azido-PEG7-NHS carbonate ester constitutes a photocleavable PEG linker featuring an azido moiety for copper-catalyzed click chemistry with alkyne, DBCO, BCN, and NHS carbonate ester to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. This structure allows for efficient photorelease of linked molecules, typically achieving over 90% cleavage in 5-25 minutes using a near-UV lamp