Lipids & Polymers

N-(Methyltetrazine-PEG4)-N-Biotin-PEG4-TFP ester is a branched biotinylation tool that enables copper-free click chemistry with a TFP ester group and a TCO reactive reagent. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. Reagent grade, for research use only.

N-(Azido-PEG2)-NH-PEG3-acid, HCl salt can undergo click chemistry reactions with propargyl, BCN or DBCO reagents. Carboxylic acid (CO2H) group is reactive with primary amino groups in the presence of EDC or HATU. Reagent grade, for research use only.

Maleimido PEG5 -NH-Boc is a PEG linker containing a maleimide group and a Boc protected amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond. Reagent grade, for research use only.

5-((pentadecan-7-yloxy)carbonyl)pentanoic acid is a lipid building block with a terminal carboxylic acid group. The acid group can derivatize amine-containing molecules in the presence of activators such as EDC or HATU. Reagent grade, for research use only.

endo-BCN-PEG2-Acrylate is a PEG linker containing a BCN group and an acrylate group. The BCN group enables copper free click chemitry with azide-tagged molecules. The acrylate group enables Michael addition reactions. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research use only.

DBCO-PEG4-PABA is an analog of DBCO-Acid with PEG linker and a 4-Aminobenzoic acid (PABA) group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain allows for increased water solubility. Reagent grade, for research use only.

TCO-PEG12-TCO is a PEG reagent containing TCO moiety at both ends of the molecule. TCO group specifically and efficiently reacts with tetrazine. The hydrophilic PEG12 arm increases the solubility of compounds in aqueous media. Reagent grade, for research use only.

N-(Acid-PEG36-PEG3-)-N-bis(PEG3-biotin) is a branched biotin linker that can be used for protein labeling. The carboxylic acid group can react with primary amines in the presence of activators such as EDC and HATU. The hydrophilic PEG branch increases the water solubility of the compound. Reagent grade, for research use only.

3-Hydroxy-2-(hydroxymethyl)propyl 6-bromohexanoate is a branched PEG linker with bromine and hydroxyl moieties. The alcohol groups can react to further derivatize the compound. The bromine (Br) is a very good leaving group for nucleophilic substitution reactions. Reagent grade, for research use only.