Extra Cellular Matrix

TissueSpec® Kidney Hydrogel is an extracellular matrix product comprised of collagens and other ECM molecules of kidney-specific origin. TissueSpec® hydrogels provide kidney cells a soft, physiologic substrate for 3D cell culture to enhance cell function and cell-cell interactions.The hydrogel format is highly versatile and can be used to culture cells on thin gels or embeed cells or organoids within thick gels.

Human Diseased NativeCoat™ Lung ECM Surface Coating is used to functionalize cell culture surfaces with human-derived diseased lung-specific extracellular matrix proteins.

Human Diseased NativeCoat™ Liver ECM Surface Coating is used to functionalize cell culture surfaces with human-derived diseased liver-specific extracellular matrix proteins.

TissueSpec® Bone ECM Hydrogel is an extracellular matrix product comprised of collagens and other ECM molecules of bone-specific origin. TissueSpec® hydrogels provide bone cells a soft, physiologic substrate for 3D cell culture to enhance cell function and cell-cell interactions.The hydrogel format is highly versatile and can be used to culture cells on thin gels or embeed cells or organoids within thick gels.

NativeCoat™ Bone ECM Surface Coating is used to functionalize cell culture surfaces with bone-specific extracellular matrix proteins. Coating with tissue-specific biochemical composition of the native cell microenvironemnt results in increased cell attachment, viability and proliferation as well as enhanced function and activation of signaling pathways.

NativeCoat™ Heart ECM Surface Coating is used to functionalize cell culture surfaces with heart-specific extracellular matrix proteins. Coating with tissue-specific biochemical composition of the native cell microenvironemnt results in increased cell attachment, viability and proliferation as well as enhanced function and activation of signaling pathways.

NativeCoat™ Intestine ECM Surface Coating is used to functionalize cell culture surfaces with intestine-specific extracellular matrix proteins. Coating with tissue-specific biochemical composition of the native cell microenvironemnt results in increased cell attachment, viability and proliferation as well as enhanced function and activation of signaling pathways.

In order to enable physiologically-relevant studies of metastatic tumor colonization or dormancy as well as accelerate drug development, Xylyx Bio offers the IN SITE™ Metastasis Kit that incorporates bone, liver, and lung extracellular matrices to provide tissue-specific composition and key extracellular features of the metastatic secondary site microenvironments. IN SITE™ Metastasis Kit provides greater control over the tumor microenvironment in vitro and represents the best platform to study carcinogenesis, migration, and metastasis or test therapeutic interventions in native ECM environments.

TissueSpec® Skin ECM Hydrogel is an extracellular matrix product comprised of collagens and other ECM molecules of skin-specific origin. TissueSpec® hydrogels provide lung cells a soft, physiologic substrate for 3D cell culture to enhance cell function and cell-cell interactions.The hydrogel format is highly versatile and can be used to culture cells on thin gels or embeed cells or organoids within thick gels.