Results for Cell Line ( 2734 )
- From: £12,469.00
Please note this product may be subject to fees, we invite you to contact your local office. MAGE-A1 CD8<sup>+</sup> NFAT-Luciferase Reporter Jurkat Cell Line was generated from T Cell Receptor (TCR) Knockout NFAT Luciferase Reporter Jurkat Cell Line (BPS Bioscience #78556) by overexpression of human CD8 (NM_001768.6) and MAGE-A1 (Melanoma-associated antigen 1) TCR using lentiviral transduction (with CD8a Lentivirus #78648 and MAGE-A1-Specific TCR Lentivirus #78934). This human MAGE-A1 TCR specifically recognizes antigen MAGE-A1 peptide, amino acids 278-286 (KVLEYVIKV). <p style="text-align: center;"><img src="{{media url="wysiwyg/82304-1.png"}}" alt="" width="531" height="306" /> Figure 1: Illustration of the functional co-culture assay used to validate the MAGE-A1 TCR CD8<sup>+</sup> NFAT-Luciferase Reporter Jurkat Cell Line.
- From: £16,338.00
Please note this product may be subject to fees, we invite you to contact your local office. ADAR1 Activity TWO-Luciferase Reporter HEK293 Cell Line is a HEK293 cell line designed to monitor cell viability in parallel with ADAR1 (adenosine deaminase acting on RNA) enzyme activity. These cells were engineered to express ADAR1 (NM_001111.5) and an ADAR1 reporter construct. This construct is comprised of an ADAR1 hairpin target with a stop codon (UAG) susceptible to ADAR1-mediated editing to tryptophan (UUG), located upstream of a firefly luciferase reporter. In addition, they constitutively express Renilla Luciferase under the control of a CMV promoter, which can be used to determine cell viability. This cell line has been validated by treatment with ADAR1 siRNA and the ADAR1 inhibitor Fludarabine. The ADAR1 reporter construct is comprised of an ADAR1 hairpin target with a stop codon (UAG) upstream of the sequence encoding firefly luciferase. In the absence of ADAR1, firefly luciferase i
- From: £12,469.00
Please note this product may be subject to fees, we invite you to contact your local office. KRAS G12D TCR (Clone 10) CD8<sup>+</sup> NFAT-Luciferase Reporter Jurkat Cell Line was generated from T Cell Receptor (TCR) Knockout NFAT Luciferase Reporter Jurkat Cell Line (BPS Bioscience #78556) by overexpression of human CD8 (NM_001768.6) and KRAS (Kirsten sat sarcoma virus) G12D TCR (Clone 10) using lentiviral transduction (with CD8a Lentivirus #78648 and KRAS G12D Specific TCR Lentivirus (Clone 10) #78937). This TCR specifically recognizes the antigen KRAS G12D Peptide, amino acids 10-19 (GADGVGKSAL, 10mer). Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.
- From: £12,469.00
Please note this product may be subject to fees, we invite you to contact your local office. KRAS G12D TCR (Clone 10) CD8<sup>+</sup> NFAT-Luciferase Reporter Jurkat Cell Line was generated from T Cell Receptor (TCR) Knockout NFAT Luciferase Reporter Jurkat Cell Line (BPS Bioscience #78556) by overexpression of human CD8 (NM_001768.6) and KRAS (Kirsten sat sarcoma virus) G12D TCR (Clone 10) using lentiviral transduction (with CD8a Lentivirus #78648 and KRAS G12D Specific TCR Lentivirus (Clone 10) #78937). This TCR specifically recognizes the antigen KRAS G12D Peptide, amino acids 10-19 (GADGVGKSAL, 10mer). Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.
- From: £12,469.00
Please note this product may be subject to fees, we invite you to contact your local office. Vγ9Vδ2 TCR NFAT-Luciferase Reporter Jurkat Cell Line was generated from T Cell Receptor (TCR) Knockout NFAT Luciferase Reporter Jurkat Cell Line (#78556) by overexpression of human Vγ9Vδ2 TCR using lentiviral transduction (with Vγ9Vδ2 TCR Lentivirus, #78985). This cell line was functionally validated with a TCR Vδ2 agonist antibody.