Cell Line

Please note this product may be subject to fees, we invite you to contact your local office. NF-κB TWO-Luciferase Reporter HEK293 Cell Line is a HEK293 cell line designed to monitor cell viability alongside NF-κB (nuclear factor Kappa B) activity. It contains a firefly luciferase reporter driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. In addition, this cell line constitutively expresses Renilla Luciferase under the control of a CMV promoter, which can be used to determine cell viability. This cell has been validated with TNFα (tumor necrosis factor alpha), and the inhibitor IKK-16 dihydrochloride.

Please note this product may be subject to fees, we invite you to contact your local office. NK Medium, Serum-Free is an optimized serum-free cell culture medium designed to culture primary NK cells with improved transduction efficiency, cell viability and expansion after engineering.  

Please note this product may be subject to fees, we invite you to contact your local office. NK Medium, Serum-Free is an optimized serum-free cell culture medium designed to culture primary NK cells with improved transduction efficiency, cell viability and expansion after engineering.  

Please note this product may be subject to fees, we invite you to contact your local office. CD20 Knockout Raji Cell Line is a Raji cell line where CD20 (B-lymphocyte antigen CD20, or MS4A1) has been genetically removed from Raji cells using CRISPR/Cas9 genome editing. This cell line has been validated by genome sequencing and flow cytometry.

Please note this product may be subject to fees, we invite you to contact your local office. CD19/CD20 Double Knockout Raji Cell Line is a Raji cell line where CD19 (Cluster of Differentiation 19, B-lymphocyte surface antigen B4, or CVID3) and CD20 (B-lymphocyte antigen CD20, or MS4A1) have been genetically removed from Raji cells using CRISPR/Cas9 genome editing. This cell line has been validated by genome sequencing and flow cytometry.

Please note this product may be subject to fees, we invite you to contact your local office. PTK7 CHO Cell Line is a CHO-K1 cell line expressing PTK7 (Protein Tyrosine Kinase 7) (NM_002821.5) under the control of a cytomegalovirus (CMV) promoter. This cell line was generated by lentiviral transduction followed by puromycin selection and limited dilution. Individual clones were screened for PTK7 expression levels by flow cytometry and a high expressing clone was selected to generate this cell line.

Please note this product may be subject to fees, we invite you to contact your local office. MUC1 CHO Cell Line is a CHO-K1 cell line expressing MUC1 variant 2 (also known as Mucin-1 or CD227; NM_001018016.3) under the control of a cytomegalovirus (CMV) promoter. This cell line was generated by lipid-mediated transfection followed by geneticin selection and limited dilution. Individual clones were screened for MUC1 expression levels by flow cytometry, and a clone was selected to generate this cell line.

The Wild type Parental RKO Reference Standard is genomic DNA derived from a highly characterized diploid RKO cell line. The product can be mixed with single-point mutation reference standard to reach the target ideal variant allele frequency (VAF). This reference standard can be used to assess the performance of your NGS, sanger sequencing and qPCR assay, including the limit of detection, accuracy, and precision.

The EGFR V769-D770insASV Reference Standard is genomic DNA derived from a highly characterized homozygous diploid HCT116 cell line, genetically modified with advanced genome editing technology to include the mutation V769-D770insASV in EGFR on both chromosomes. The variant allele frequency (VAF) is 100%, and can be diluted using the corresponding wild-type standard to reach lower VAF. This reference standard can be used to assess the performance of your NGS, sanger sequencing and qPCR assay, including the limit of detection, accuracy, and precision.