Chemicals & Small Molecules

Aminooxy-PEG4-MMAF is an agent-linker combination designed for antibody-drug conjugates (ADCs), harnessing the robust antitumor efficacy of the potent anti-tubulin agent MMAF. This connection is established through the water-soluble PEG4 linkage. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-Boc-dolaproine (Dap) constitutes the amino acid component derived from the pentapeptide Dolastatin 10. Reagent grade, for research purpose.

Boc-Dap-NE, a dipeptide, serves as a detachable linker in the construction of antibody-drug conjugates (ADCs). Reagent grade, for research purpose.

VCP-Eribulin comprises the ADC linker (VCP) and Eribulin. Eribulin is a distinctive microtubule inhibitor. VCP-Eribulin represents an Eribulin-derived component designed for antibody-drug conjugates.

Mal-(CH2)5-Val-Cit-PAB-Eribulin is an agent-linker conjugate designed for antibody-drug conjugates (ADCs) and demonstrates robust antitumor activity. It incorporates the anti-microtubule agent Eribulin, which is employed in the study of metastatic breast cancer.

Trabectedin, sanctioned as an alkylating agent, is authorized for the management of unresectable or metastatic soft tissue sarcoma, specifically liposarcoma or leiomyosarcoma. Reagent grade, for research purpose.

Lurbinectedin (PM01183) acts as a potent anti-tumor agent by binding covalently to the DNA minor groove. Its role is crucial in the creation of antibody drug conjugates (ADCs), where it serves as a cytotoxic payload. Reagent grade, for research purpose.

alpha-Amanitin is an inhibitor of RNA polymerase II and may be employed as a payload in the development of antibody drug conjugates (ADCs). Reagent grade, for research purpose.

Duocarmycin TM (CBI-TMI) functions as a robust antitumor antibiotic with the capability to induce sequence-selective alkylation of duplex DNA. Its crucial role lies in serving as a cytotoxic payload during the development of antibody drug conjugates (ADCs). Reagent grade, for research purpose.