Results for Labelling ( 3144 )
- From: £503.00
Our CELT-145 ligand is a highly potent fluorescent antagonist developed for hA1R testing with a Ki of 160 nM in radioligand binding assay. The product comes in a 10ug vial that enables the preparation of 63ml of 100nM working solution to test AT1R. Our fluorescent antagonist is ideal for visualization in confocal microscopy and high-content system experiments. Our CELT-145 ligand is potentially suitable for other fluorescence-based assays such as HTRF.
- From: £291.00
Our potent CELT-150 VHL E3 ligase fluorescent ligand is a tracer for VHL E3 ligases binding assays, designed to perform affinity binding curves to VHL protein using TR-FRET homogenous technology. Von Hippel–Lindau protein (VHL) is the substrate recognition subunit of an E3 ligase recruited by bifunctional Proteolysis-targeting chimeras (PROTACs) to induce ubiquitination and subsequent proteasomal degradation of a targeted protein.
- From: £503.00
Our hA3 Adenosine receptor fluorescent antagonist shows a high affinity and selectivity for A3 receptor over the other receptor subtypes (Ki =6.13 nM for A3 receptor in radioligand binding assay). It allows to perform cell visualization in fluorescence microscopy, confocal microscopy and high content system experiments. It is potentially suitable for other fluorescence-based assays.
- From: £503.00
Our hD2 Dopamine receptor fluorescent antagonist shows high affinity for hD2 receptor and selectivity over the other receptor subtypes (Ki =1.06 nM for hD2 receptor in radioligand binding assay). It allows to perform cell visualization in fluorescence microscopy, confocal microscopy and high content system experiments. It is potentially suitable for other fluorescence-based assays.
- From: £503.00
Our h5HT2B Serotonin receptor fluorescent ligand shows a high affinity for 5HT2B serotonin receptor and high selectivity over the other receptor subtypes (Ki =56.32 nM for 5HT2B receptor in radioligand binding assay).It allows to perform cell visualization in fluorescence microscopy, confocal microscopy and high content system experiments. It is potentially suitable for other fluorescence-based assays.
- From: £503.00
Our CELT-252 ligand is a highly potent fluorescent antagonist developed for hA1R testing with a Ki of 39 nM in radioligand binding assay. The product comes in a 10ug vial that enables the preparation of 69ml of 100nM working solution to test AT1R. Our fluorescent antagonist is ideal for visualization in confocal microscopy and high-content system experiments. Our CELT-252 ligand is potentially suitable for other fluorescence-based assays such as Fluorescence Polarization.
- From: £503.00
Our h5HT2A/5HT2C Serotonin receptor fluorescent antagonist shows a high affinity for h5HT2A/h5HT2C serotonin receptors (Ki =29.7 nM and 14.6 nM respectively in radioligand binding assay).It allows to perform cell visualization in fluorescence microscopy, confocal microscopy and high content system experiments. It is potentially suitable for other fluorescence-based assays.
- From: £503.00
Our hD2 Dopamine receptor fluorescent antagonist shows high affinity for hD2 receptor and partial selectivity over the other receptor subtypes (Ki =89.3 nM for hD2 receptor in radioligand binding assay). It has been validated in Fluorescence Polarization binding assays as a valid alternative to radioligand binding assays.It allows to perform cell visualization in fluorescence microscopy, confocal microscopy and high content system experiments. It is potentially suitable for other fluorescence-based assays.
- From: £503.00
Our potent Sigma h σ1/σ2 receptor fluorescent ligand is available in a 10ug vial, allowing you to prepare 103 ml of 100nM working solution to test σ1/σ2 receptors. Our CELT-483 product has been specifically designed to meet the needs of researchers in a variety of fields, enabling the study of σ1 and σ2 receptors with accuracy and precision. It has been validated in flow cytometry (Kd=13,59 nM for σ2) and confocal microcopy in MCF7 cell lines (see publication for more details) to study both σ1 and σ2 receptors, using the appropriate masking agent.