PEG

Thiol-PEG4-acid is a PEG linker containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-PEG4-amine is an aqueous soluble PEGylation reagent containing a free amine and a methyltetrazine group. Methyl group improves the stability and hydrophilic PEG spacer increases water-solubility. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-mPEG, MW 5,000 is a click chemistry PEG polymer which can react with azides via a copper-free click chemistry to form a stable triazole linkage. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Sulfo DBCO-Amine can be used to derivatize carboxyl-containing molecules or activated esters (e.g. The NHS ester) with DBCO moiety through a stable amide bond. The low mass weight will add minimal spacer to modified molecules and the hydrophilic sulfonated spacer arm will greatly improve water solubility of DBCO derivatized molecules. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azido-PEG24-NHS ester is a monodisperse, high purity PEG linker. The azide group enables Click Chemistry. The NHS ester can be used to label the primary amines (-NH2) of proteins, oligonucleotides, and other amine-containing biomolecules. The hydrophilic PEG spacer adds to the water solubility of this reagent. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-PEG8-NHS Ester is a click chemistry molecule cosisting of an NHS ester that is reactive specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. PEG8 spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-(Amino-PEG10)-N-bis(PEG10-azide) is a PEG reagent containing a terminal amine and two azide groups. The hydrophilic PEG spacer increases solubility in aqueous media. The azide groups can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

(Amino-PEG10)-Tri-(Azide-PEG10-ethoxymethyl)-methane HCl Salt is a branched PEGylation reagent containing an amino group with three azide groups. The amino group is reactive with carboxylic acids, activated NHS esters. . The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Amino-PEG-t-butyl ester, MW 3,400 is a coupling PEG reagent which can be reacted with a succinimidyl ester under physiological condition to form an amide bond. The t-butyl ester group can be hydrolyzed under acidic or basic condition. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.