PEG

4-(N-methyl-N-phenylamino)butanoic NHS ester is a short linker featuring a methylaniline and an NHS ester. The NHS is a good leaving group which is easily displaced by nucleophiles while methylaniline is a highly electron-dense heterocycle with a variety of chemical uses.

m-PEG-bromide, MW 5,000 is a large PEG molecule containing a methoxy and a bromide. The methoxy group caps one end of the molecule to allow the PEGylation of a target molecule to proceed on only one end of this molecule at the terminal bromide. PEG linkers with high molecular weights such as this one are frequently employed in developing PEG-lipid conjugates such as the ones used to create lipid nanoparticles for drug delivery.

N-Methylaniline-PEG3-TCO is a short PEG linker featuring a methylaniline and a TCO group. TCO is a click chemistry handle which readily reacts with tetrazine-containing compounds while methylaniline is a highly electron-dense heterocycle with a variety of chemical applications.

N-Methylaniline-PEG3-methyltetrazine is a short PEG linker featuring a methylaniline and a methyltetrazine group. Methyltetrazine is a click chemistry motif which readily reacts with TCO-containing compounds while methylaniline is a highly electron-dense heterocycle with a variety of applications.

t-Boc-Aminooxy-PEG7-azide is a short bifunctional PEG linker featuring an azide and a Boc-protected amine. Azides readily react with alkynes through click chemistry, while the Boc protecting group can be removed using strong acid.

Dimethylanaline-PEG4-acid is a short PEG linker featuring a carboxylic acid and a methylaniline. Carboxylic acids can be linked to alcohols or amines while methylaniline is a highly electron-dense aromatic ring with a wide variety of chemical uses.

Bromo-PEG-bromide, MW 2,000 is a polyPEG linker containing two bromide groups. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.

Azido-PEG5-azide is an aqueous soluble, homobifunctional PEG reagent. The azide (N3) group is very reactive with alkynes such as BCN, DBCO via Click Chemistry to yield a stable triazole moiety.

1-(2-hydroxymethyl)-1-H-pyrrole-2,5-dione is a synthetic building block for adding an maleimide group with a hydroxyl handle. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.