PEG

DBCO-PEG6-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Biotin-PEG5-alcohol is a biotinylation reagent containing a primary hydroxyl that can be derivatized. The PEG spacer provides greater solubility to labeled molecules compared to reagents having only hydrocarbon spacers.

DMG-PEG2000

DMG-PEG2000

Maleimide PEG NHS, MP 10,000

Diethyl 6-bromohexylphosphonate is a short linker featuring a bromide and a diethyl phosphonate. The bromide is a good leaving group which can be easily displaced by nucleophiles like alcohols, amines or thiols, while the diethyl phosphonate may be hydrolyzed to allow for esterification.

DOTA(OtBu)3 contains a DOTA moiety with t-butyl groups which can be used as a chelating agent for cations and is commonly used for imaging diagnostics. The t-butyl protected carboxyl group can be deprotected under acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Lenalidomide-OH is a E3 ligase activator used in the development of PROTACs.

E3 ligase Ligand 19 is small molecule used in the development of PROTACs.