PEG

PLGA(10k)-PEG(2k)-DBCO is an cyclooctyne terminated block copolymer with hydrophobic poly(lactide-co-glycolide) (PLGA) and hydrophilic PEG blocks. The DBCO can react with azide readily (Cu-free) to form a covalent triazole bond. The biodegradable polymer can be used to prepare drug-loaded nanoparticles for drug delivery. Reagent grade, for research purpose.

PLGA(10k)-PEG(5k)-DBCO is an amphiphilic block copolymer with terminal DBCO moiety for click chemistry with azido molecule via SPAAC. The polymer can form micelles in water with core and shell made of poly(lactide-co-glycolide) (PLGA) and PEG, respectively. It can be used to encapsulate hydrophobic drugs. Reagent grade, for research purpose.

PLGA(40k)-PEG(5k)-DBCO is a polymer with both hydrophobic (poly(lactide-co-glycolide)/PLGA) and hydrophilic (PEG) blocks. The self-assembly of the polymer in water occurs with PLGA being shielded at the core by PEG shell. The hydrophobic core can be used to encapsulate lipophilic drugs while the PEG shell offers protection against (enzymatic/hydrolysis) degradation in drug delivery/nanomedicine. The DBCO is reactive with azide via copper-free click chemistry to form a stable triazole bond. Reagent grade, for research purpose.

PLGA(2k)-PEG(1k)-MAL is a thiol reactive amphiphilic polymer. The conjugation between maleimide and thiol forms a stable thioether bond. The polymer contains a hydrophobic block (poly(lactide-co-glycolide) (PLGA)) and a hydrophilic block (PEG) which can form micelles in water. This class of polymer can be used to prepare vesicle for drug delivery application. Reagent grade, for research purpose.

PLGA(2k)-PEG(2k)-MAL is an amphiphilic block copolymer with hydrophobic block made of poly(lactide-co-glycolide) (PLGA) tethered to a hydrophilic PEG. It can self-assemble in aqueous media to form micelles and be used to prepare nanoparticles for drug encapsulation in nanomedicine/drug delivery. The maleimide is reactive with thiol molecule at pH 6.5-7.5 to form a stable thioether bond. Reagent grade, for research purpose.

PLGA(5k)-PEG(2k)-MAL is a self-assembling block copolymer with poly(lactide-co-glycolide) (PLGA) as hydrophobic segment and PEG as hydrophilic block. The maleimide is reactive with thiol molecule to form a stable thioether linkage. The polymer can be used to prepare drug loaded nanoparticles for targeted delivery. Reagent grade, for research purpose.

PLGA(10k)-PEG(5k)-MAL is a maleimide terminated amphiphilic polymer which can react with thiol (SH) at pH 6.5-7.5 via formation of thioether linkage. In water, the polymer self assembles to form micelles with poly(lactide-co-glycolide) (PLGA) core being shielded from the water by PEG shell. The polymer can be used to prepare drug loaded nanoparticles for drug delivery. Reagent grade, for research purpose.

PLGA(20k)-PEG(3k)-MAL has terminal maleimide which can react with thiol molecule via thioether bond formation. The polymer forms micelles in water where the core contains poly(lactide-co-glycolide) (PLGA) and the shell is made of PEG. This polymer can be used to prepare nanocarrier for therapeutic agents/drugs. Reagent grade, for research purpose.

PLGA(20k)-PEG(5k)-MAL is a block copolymer containing poly(lactide-co-glycolide) (PLGA) (hydrophobic) and PEG (hydrophilic). Upon dispersion in water, the polymer self-assembles to form micelles with PLGA core and PEG shell. The core can be used as reservoir for hydrophobic drugs while the shell can provide protection from degradation (enzymatic/hydrolysis). The terminal maleimide is reactive with thiol (SH) at physiological pH 6.5-7.5 via thioether bond formation. Reagent grade, for research purpose.