Results for DNA & Clones ( 1199 )
- From: £6,046.00
DNA was prepared from cell line WM1799. WM1799 is a metastatic human melanoma cell line. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line also expresses PTEN loss of function including hemizygous deletion and is wild type for N-RAS, c-KIT, and CDK4. WM1799 cells produce xenograft tumors when injected into immunocompromised mice.
- From: £1,806.00
DNA was prepared from cell line WM1819. WM1819 is a human melanoma cell line that displays mesenchymal morphology. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. WM1819 cells produce xenograft tumors when injected into immunocompromised mice.
- From: £6,046.00
DNA was prepared from cell line WM1819. WM1819 is a human melanoma cell line that displays mesenchymal morphology. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. WM1819 cells produce xenograft tumors when injected into immunocompromised mice.
- From: £1,806.00
DNA was prepared from cell line WM1852. WM1852 is a metastatic human melanoma cell line that displays mesenchymal and spherical morphology. These cells require 10% media to adhere to culture dish. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. WM1852 cells produce xenograft tumors when injected into immunocompromised mice.
- From: £6,046.00
DNA was prepared from cell line WM1852. WM1852 is a metastatic human melanoma cell line that displays mesenchymal and spherical morphology. These cells require 10% media to adhere to culture dish. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. WM1852 cells produce xenograft tumors when injected into immunocompromised mice.
- From: £1,806.00
DNA was prepared from cell line WM1862. WM1862 is a non-tumorigenic (RGP) primary human melanoma cell line without metastatic capability. This cell line displays pigmented, mesenchymal and spherical morphology. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. These cells expresses wild type N-RAS, c-KIT, and CDK4. WM1862 cells produce xenograft tumors when injected into immunocompromised mice.