Chemicals & Small Molecules

HA850-BODIPY-FL is made up of hyaluronic acid labeled with the green fluorophore Bodipy®-FLAverage MW: 700-800 kDaDegree of Substitution: 0.5-2.0 labels per polymer chainHyaluronic acid (HA) is a high molecular weight anionic polysaccharide (1 000-10 000 kD) composed of repeating disaccharides and is one of several glycosaminoglycan components of the extracellular matrix of connective tissue. Free HA is taken up by the liver where it is degraded and recycled. Many chronic liver diseases including infection (hepatitis B or C) toxicity (alcohol and drugs) genetic (hemochromatosis) autoimmunity and malignancy result in liver inflammation which can progress to liver fibrosis and cirrhosis; causing impairment of liver function and resulting in a rapid increase in circulating HA levels. Data indicates a relationship between HA levels local inflammation and severity of disease. Recent publications have also shown that HA levels in urine are indicative of bladder cancer that HA levels

HA850-TexasRed is made up of hyaluronic acid labeled with the red fluorophore Texas RedAverage MW: 700-800 kDaDegree of Substitution: 0.5-2.0 labels per polymer chainHyaluronic acid (HA) is a high molecular weight anionic polysaccharide (1 000-10 000 kD) composed of repeating disaccharides and is one of several glycosaminoglycan components of the extracellular matrix of connective tissue. Free HA is taken up by the liver where it is degraded and recycled. Many chronic liver diseases including infection (hepatitis B or C) toxicity (alcohol and drugs) genetic (hemochromatosis) autoimmunity and malignancy result in liver inflammation which can progress to liver fibrosis and cirrhosis; causing impairment of liver function and resulting in a rapid increase in circulating HA levels. Data indicates a relationship between HA levels local inflammation and severity of disease. Recent publications have also shown that HA levels in urine are indicative of bladder cancer that HA levels are

Isopentenyl diphosphate (IPP) is a building block in the isoprenoid biosynthesis pathway. Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes fungi and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway.Provided as the tris-ammonium saltAlternate Names: Isopentenyl pyrophosphate IPPBulk discounts available please email echelon@echelon-inc.com for information. Powered by Bioz See more details on Bioz

Dimethylallyl diphosphate (DMAPP) is a building block in the isoprenoid biosynthesis pathway. Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes fungi and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway.Provided as the tris-ammonium salt Powered by Bioz See more details on Bioz

Geranyl diphosphate (GPP) is an intermediate in isoprenoid biosynthesis. Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes fungi and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway. GPP is formed by the condensation of DMAPP and IPP catalyzed by geranyl diphosphate synthase.Provided as the tris-ammonium salt Powered by Bioz See more details on Bioz

Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes fungi and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway. Neryl diphosphate is a precursor for monoterpenes such as mycrene and cyclic monoterpenes such as limonene.Provided as the tris-ammonium salt

Trans trans-farnesyl diphosphate (FPP) is an intermediate in isoprenoid biosynthesis. Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes fungi and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway. FPP is formed by the condensation of DMAPP with two units of IPP catalyzed by farnesyl diphosphate synthase.Provided as the tris-ammonium salt Powered by Bioz See more details on Bioz

Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes fungi and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway. 2Z 6Z-Farnesyl diphosphate is synthesized by Z-farnesyl diphosphate synthase (M. tuberculosis) from neryl diphosphate.  It is not a substrate for protein-farnesyl transferase.Provided as the tris-ammonium salt.

Geranylgeranyl diphosphate (GGPP) is an intermediate in isoprenoid biosynthesis. Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes fungi and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway. GGPP is formed by the addition of IPP to farnesyl diphosphate catalyzed by geranylgeranyl diphosphate synthase.Provided as the tris-ammonium salt Powered by Bioz See more details on Bioz