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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 97587 )

      • Doxapram

        Ref: T22315
        Sizes: 10 mg
        From: £28.00

        Doxapram (Legacy Tebubio ref. 282T22315). Doxapram (Dopram) is a respiratory stimulant that inhibits TASK-1, TASK-3, and TASK-1/TASK-3 heterodimer channels and is used to study ventilatory failure caused by apnea of ​​prematurity and exacerbation of chronic obstructive pulmonary disease.

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      • Doxazosin

        Ref: T22316
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: £39.00

        Doxazosin (Legacy Tebubio ref. 282T22316). Doxazosin (UK 33274) is a long-acting α1-adrenoceptor inhibitor widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms.

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      • DRB18

        Ref: T22317
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: £91.00

        DRB18 (Legacy Tebubio ref. 282T22317). DRB18 is a highly effective pan-class inhibitor of glucose transporter proteins (GLUT). It significantly modulates energy-related metabolism in A549 cells by inducing alterations in the abundance of metabolites associated with glucose-related pathways. DRB18 exerts its effects by promoting G1/S phase arrest, increasing oxidative stress, and prompting necrotic cell death, ultimately displaying notable anti-tumor activity [1].

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      • Taletrectinib

        Ref: T22318
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: £65.00

        Taletrectinib (Legacy Tebubio ref. 282T22318). Taletrectinib (AB-106) is a new-generation selective inhibitor of ROS1/NTRK including ROS1,NTRK1,NTRK2 and NTRK3 with IC50 of 0.207 nM,0.622 nM,2.28 nM and 0.980 nM, respectively.

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      • DTP3

        Ref: T22319
        Sizes: 5 mg, 10 mg, 2 mg
        From: £73.00

        DTP3 (Legacy Tebubio ref. 282T22319). DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.

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      • JNJ-7777120

        Ref: T2232
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: £61.00

        JNJ-7777120 (Legacy Tebubio ref. 282T2232). JNJ-7777120 is the first potent and selective non-imidazole histamine H4 receptor antagonist with Ki of 4.5 nM, exhibits >1000-fold selectivity over the other histamin receptors.

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      • edetate calcium disodium

        Ref: T22321
        Sizes: 25 mg, 100 mg, 50 mg, 10 mg, 200 mg
        From: £33.00

        edetate calcium disodium (Legacy Tebubio ref. 282T22321). Edetate calcium disodium(EDTA calcium disodium) , a chelating agent, is primarily used for the management of severe lead poisoning.

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      • EEDi-5285

        Ref: T22322
        Sizes: 5 mg, 25 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        Price Enquiry

        EEDi-5285 (Legacy Tebubio ref. 282T22322). EEDi-5285, an orally active and highly potent inhibitor targeting embryonic ectoderm development (EED) protein, exhibits anti-cancer activity. It demonstrates exceptional efficacy with an IC50 value of 0.2 nM, indicating robust binding affinity to the EED protein.

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      • Enoxaparin sodium

        Ref: T22323
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 2 mg
        From: £30.00

        Enoxaparin sodium (Legacy Tebubio ref. 282T22323). Enoxaparin sodium is a low-molecular-weight heparin (LMWH) that has recently been approved by the US FDA for use in patients with medically managed ST-segment myocardial infarction (STEMI), or STEMI with subsequent percutaneous coronary intervention (PCI). It binds to and potentiates the action of antithrombin, and inhibits coagulation factors XIa, IXa, Xa and IIa (thrombin), thereby preventing formation of blood clots.

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