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Results for Chemicals & Small Molecules ( 97562 )
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(±)-Anatoxin A fumarate (Legacy Tebubio ref. 282T22478). (±)-Anatoxin A fumarate is a natural alkaloid isolated from freshwater cyanobacterium. It acts as a potent nicotinic receptor agonist, exhibiting Ki values of 1.25 nM and 1.84 μM for binding to α4β2-type nAChR and α7-type nAChR in rat brain membranes, respectively. (±)-Anatoxin A fumarate stimulates [3H]-dopamine release from rat striatal synaptosomes with an EC50 of 134 nM.