Chemicals & Small Molecules

Biotin-SLC-NHS Ester is membrane-permeable which allows it to be used for intracellular labeling. NHS group can react efficiently with primary amino groups (-NH2) to form stable, irreversible amide bonds. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

This is a hydrazide-activated biotinylation reagent used to label glycoproteins, carbohydrate-containing compounds that have oxidizable sugars or aldehydes. Hydrazine moiety reacts with an aldehyde to form semi-permanent hydrazone bonds. The extended spacer arm helps to minimize steric hindrance. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Gambogic acid is a natural product isolated from the resin of Garcinia hurburyi tree, Gambogic acid is a potent apoptosis inducer. It binds covalently to the regulatory subunit B (SPTSSB) of the serine palmitoyltransferase complex and inhibits de novo sphingolipid biosynthesis. Reagent grade, for research purpose.

Cy5 acid is a dye containing a non-activated carboxylic acid. This dye has limited water solubility, but can be dissolved in mixtures of water with organic phase (DMF, DMSO, alcohols) to obtain useful concentrations of the material in solution. This molecule can be considered non-reactive dye for the use in control samples, and for instrument calibration. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Cy5-NHS ester is a reactive dye containinig NHS ester group, which enables labeling of amino-bearing biomolecules. This reagent can be used for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

MMAE is a synthetic antineoplastic agent. Because of its toxicity, it cannot be used as a drug itself; instead, it is linked to a monoclonal antibody (MAB) which directs it to the cancer cells. Monomethyl auristatin E or MMAE is 100-1000 times more potent than doxorubicin. It is a very potent antimitotic agent that inhibits cell division by blocking the polymerization of tubulin. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Fmoc-Val-Cit-PAB-PNP is a a cleavable ADC linker used in antibody drug conjugate. The Val-Cit linker was designed to be cleaved by cathepsin B. PNP group is a good leaving group when reacting with amine bearing payload. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Monomethyl auristatin F (MMAF) is an antitubulin agent that inhibits cell division by blocking the polymerization of tubulin. Because of MMAF is highly toxic, it cannot be used as a drug itself. MMAF induces potent antitumor effects when conjugated via protease cleavable linkers to a monoclonal antibody targeting internalizing, tumor-specific cell surface antigens. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Cy5-PEG5-azide is a cyanine5 dye linker containing a water soluble PEG chain and an azide terminal group. The azide can undergo copper-catalyzed Click Chemistry reactions with alkynes, DCBO and BCN groups. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.