Results for Chemicals & Small Molecules ( 97561 )
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Azido-PEG5-Ala-Ala-Asn-PAB PAB is a unique peptide cleavable ADC linker for antibody-drug-conjugation, Azido group is very reactive toward DBCO, BCN or other Alkyne groups, called click chemistry. PEG spacer increases the aqueous solubility. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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Active-Mono-Sulfone-PEG8-acid is a PEG linker with a sulfone and acid end group. The sulfone group can be conjugated with thiol groups of proteins. The terminal carboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to from stable amide bonds. The hydrophilic PEG chain increases the water solubility of the compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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Bis-sulfone-PEG12-NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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Bis-sulfone-PEG4-NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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Bis-sulfone NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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Fluorescein isothiocyanate (FITC) is a yellow-orange molecule with an absorption maximum at 495nm. Upon excitation, it emits a yellow-green color with an emission maximum at 525nm. Fluorescein isothiocyanate is widely used to attach a fluorescent label to proteins via the amine group. The isothiocyanate group reacts with nucleophiles such as amino or thiol terminals. It has been used for the labeling of proteins including antibodies and lectins. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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Azido-PEG3-Val-Cit-PAB-PNP is a cleavable peptide ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. PNP groupg is a good leaving group when treating with aminebearing payload. Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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diSulfo-Cy3 azide is a water-soluble dye containing an alkyne group, which enables Click Chemistry. Absorbance and emission of the dye are identical to Cy3 fluorophore. The reagent is designed for the labeling of proteins, and even intact biological objects in water phase. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.