Chemicals & Small Molecules

Juvenile Hormone III (JH III) is a sesquiterpanoid found in insects which regulates important physiological processes such as reproduction and metamorphosis. JH III is biosynthesized via the mevalonate pathway and is metabolized by JH esterase and JH epoxide hydrolase terminating the activity of the hormone. JH III has also been found in certain plants such as Cyperus iria and C. Aromaticus potentially acting as a protectant against insect herbivory.

Bisepoxy Juvenile Hormone III (mixture of diastereomers) is a sesquiterpenoid biosynthesized via the mevalonate pathway in the ring-glands of higher dipterans. Juvenile Hormones are sesquiterpenoids found in insects that regulates important physiological processes such as reproduction and metamorphosis. Bisepoxy juvenile hormone III (JHB3) is biosynthesized via the mevalonate pathway in the ring-glands of higher dipterans (flies).

Propargyl-farnesol is an alkyne-modified isoprenoid that acts as a chemical reporter of protein prenylation via "Click" chemistry.The alkyne-modified isoprenoids were developed by the Distefano group at the University of Minnesota as chemical reporters of protein prenylation. The isoprenoids readily penetrate mammalian cells and are used as substrates by prenyltransferases. The pendant alkyne can be derivatized with an azide-containing tag such as a fluorophore or biotin via a Cu(I) catalyzed “Click” reaction allowing the prenylated proteins to be identified and quantified.

Isoprenoids and isoprenols are key metabolic intermediates for biosynthesis of steroids including cholesterol and hormones that regulate human reproduction or fertility and post-translational modifications of proteins in signal transduction pathways for cell division and regulation of vesicular trafficking.

(E E E)-Geranylgeraniol is an intermediate in the biosynthetic pathway of vitamins E & K and is linked to proteins via post-translational modification. Powered by Bioz See more details on BiozKeywords: (2E 6E 10E)-3 7 11 15-tetramethylhexadecatetra-2 6 10 14-en-1-ol

Squalene is a naturally occurring triterpenoid synthesized from two molecules of farnesyl diphosphate (FPP) by squalene synthase. Squalene is used as an adjuvant in vaccine formulation. Echelon's squalene has been further purified to remove oxidized byproducts.

2 3-Oxidosqualene is an important intermediate in the biosynthesis of membrane sterols being converted to lanosterol by 2 3-oxidosqualene cyclase. The (S)-enantiomer is formed by oxidation of squalene by monooxygenase. 2 3-(R)-oxidosqualene is an inhibitor of lanosterol synthase Powered by Bioz See more details on Bioz

2 3 22 23-Dioxidosqualene (mixture of diastereomers) is a substrate for oxidosqualene cyclase forming 24 25-oxidolanosterol. Powered by Bioz See more details on Bioz

This is a laboratory product for research use only. Not for personal consumption. It will not be effective and is dangerous for personal use.